Breast cancer cell lines: Friend or foe?

Sarah E. Burdall, Andrew M. Hanby, Mark R.J. Lansdown, Valerie Speirs*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

228 Citations (Scopus)


The majority of breast cancer research is conducted using established breast cancer cell lines as in vitro models. An alternative is to use cultures established from primary breast tumours. Here, we discuss the pros and cons of using both of these models in translational breast cancer research.

Original languageEnglish
Pages (from-to)89-95
Number of pages7
JournalBreast Cancer Research
Issue number2
Publication statusPublished - 2003
Externally publishedYes


  • Cell culture
  • In vitro models
  • Mammary gland


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