Characteristics of Patients in Platform C19, a COVID-19 Research Database Combining Primary Care Electronic Health Record and Patient Reported Information

Brooklyn Stanley, Andrew Davis, Rupert Jones, Steven A. Julious, Dermot Ryan, David Jackson, David M.G. Halpin, Hilary Pinnock, Jennifer K Quint, Kamlesh Khunti, Liam G Heaney, Philip Oliver, Salman Siddiqui, Anu Kemppinen, Francis Appiagyei, Emma-Jane Roberts, Antony Hardjojo, Victoria Carter, Marije van Melle, David Price* (Corresponding Author)Platform C19 committee

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
8 Downloads (Pure)


Data to better understand and manage the COVID-19 pandemic is urgently needed. However, there are gaps in information stored within even the best routinely-collected electronic health records (EHR) including test results, remote consultations for suspected COVID-19, shielding, physical activity, mental health, and undiagnosed or untested COVID-19 patients. Observational and Pragmatic Research Institute (OPRI) Singapore and Optimum Patient Care (OPC) UK established Platform C19, a 51 research database combining EHR data and bespoke patient questionnaire. We describe the 52 demographics, clinical characteristics, patient behavior, and impact of the COVID-19 pandemic using data within Platform C19.

EHR data from Platform C19 were extracted from 14 practices across UK participating in the OPC COVID-19 Quality Improvement program on a continuous, monthly basis. Starting 7th 56 August 2020, consenting patients aged 18-85 years were invited in waves to fill an online questionnaire. Descriptive statistics were summarized using all data available up to 22nd 58 January 2021.


From 129,978 invitees, 31,033 responded. Respondents were predominantly female (59.6%), white (93.5%), and current or ex-smokers (52.6%). Testing for COVID-19 was received by 23.8% of 62 respondents, of which 7.9% received positive results. COVID-19 symptoms lasted ≥4 weeks in 19.5% of COVID-19 positive respondents. Up to 39% respondents reported a negative impact on questions regarding their mental health. Most (67%-76%) respondents with asthma, Chronic Obstructive Pulmonary Disease (COPD), diabetes, heart, or kidney disease reported no change in the condition of their diseases.

Platform C19 will enable research on key questions relating to COVID-19 pandemic not possible using EHR data alone.
Original languageEnglish
Pages (from-to)e0258689
JournalPloS ONE
Issue number10
Early online date19 Oct 2021
Publication statusPublished - 19 Oct 2021

Bibliographical note


Other members of the Platform C19 steering committee consist of Dr David Jones from Box Surgery, Prof Ian Pavord from the University of Oxford, Dr Katherine Hickman from the Primary Care Reimbursement Service, Bradford & Leeds, Sir Prof Lewis Ritchie, OBE from the University of Aberdeen, Pam Young and Tony Megaw from Wellbeing Software, and Steve Davis from Interface Clinical Services, Dr Samantha Walker from Asthma UK & British Lung Foundation, Prof Stephen Holgate from the University of Southampton and the Medical Research Council, and Sue Beacroft from Open Vie/Harvey Walsh and OPCRD-NEXUS. Medical writing of this manuscript was provided by Antony Hardjojo who is funded by Observational and Pragmatic Research Institute, Singapore. We wish to acknowledge our GP Partner Practices: Alnwick Medical Group, Guidepost Medical Group, Priory Medical Group, Highgate Medical Centre, Clifton Medical Centre, Bridge Street Surgery, Park and St Francis Surgery, Brockworth Surgery, Whitemoor Medical Centre, Tong Medical Practice, Eric Moore Partnership, Bridgewater Surgeries, The Village Surgery, and Queen Square Medical Practice


Dive into the research topics of 'Characteristics of Patients in Platform C19, a COVID-19 Research Database Combining Primary Care Electronic Health Record and Patient Reported Information'. Together they form a unique fingerprint.

Cite this