Choriocarcinoma in a postmenopausal woman

Bradley Chittenden, Eliyaz Ahamed, Abha Maheshwari

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


BACKGROUND: Choriocarcinoma typically occurs within 12 months of pregnancy but rarely may present many years after an antecedent pregnancy. This report describes choriocarcinoma in a postmenopausal woman. CASE: A 62-year-old woman presented with dyspnea, a history of postmenopausal vaginal spotting, and metastatic disease on chest X-ray. A transvaginal ultrasonogram revealed a thickened endometrium. Endometrial biopsy and an elevated beta-hCG confirmed the diagnosis of metastatic choriocarcinoma. Multiagent chemotherapy was initiated, and the patient developed fatal toxic epidermal necrolysis. CONCLUSION: This case reminds practitioners that choriocarcinoma can occur in postmenopausal women, and although cure rates are high, deaths occasionally occur because of toxicity associated with treatment.
Original languageEnglish
Pages (from-to)462-465
Number of pages4
JournalObstetrics & Gynecology
Issue number2 Pt 2
Publication statusPublished - Aug 2009


  • age factors
  • choriocarcinoma
  • fatal outcome
  • female
  • humans
  • middle aged
  • postmenopause
  • time factors
  • uterine neoplasms


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