Crystal structure of 4-hydroxy-3-meth-oxybenzaldehyde 4-methylthiosemi-carbazone methanol monosolvate

Adriano Bof De Oliveira*, Johannes Beck, Christian Landvogt, Barbara Regina Santos Feitosa, W. T A Harrison (Editor)

*Corresponding author for this work

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In the title solvate, C15H15N3O2S·CH3OH, the thio-semicarbazone molecule is approximately planar; the maximum deviation from the mean plane is 0.4659 (14) Å and the dihedral angle between the aromatic rings is 9.83 (8)°. This conformation is supported by an intramolecular N - H⋯N hydrogen bond. In the crystal, the thiosemicarbazone molecules are linked into dimers by pairs of N - H⋯S hydrogen bonds, thereby generating R22(8) loops. The methanol solvent molecule bonds to the thiosemicarbazone molecule through a bifurcated O - H⋯(O,O) hydrogen bond and also accepts an O - H⋯O link from the thiosemicarbazone molecule. Together, these links generate a three-dimensional network.

Original languageEnglish
Pages (from-to)o313-o314
Number of pages2
JournalActa Crystallographica Section E: Structure Reports Online
Issue number5
Early online date18 Apr 2015
Publication statusPublished - 1 May 2015

Bibliographical note

BRSF thanks CNPq/UFS for the award of a PIBIC scholarship.


  • Bifurcated hydrogen bond
  • Crystal structure
  • Thiosemicarbazone derivative from natural product (vanillin)


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