Abstract
Background: Multimorbidity, the coexistence of multiple health conditions, is a growing public health challenge. Research and intervention development are hampered by the lack of consensus regarding defining and measuring multimorbidity. The aim of this systematic review was to pool the findings of systematic reviews examining definitions and measures of multimorbidity.
Methods: Medline, Embase, PubMed and Cochrane were searched from database inception to February 2017. Two authors independently screened titles, abstracts and full texts and extracted data from the included papers. Disagreements were resolved with a third author. Reviews were quality assessed.
Results: Of six reviews, two focussed on definitions and four on measures. Multimorbidity was commonly defined as the presence of multiple diseases or conditions, often with a cut-off of two or more. One review developed a holistic definition including biopsychosocial and somatic factors as well as disease. Reviews recommended using measures validated for the outcome of interest. Disease counts are an alternative if no validated measure exists.
Conclusions: To enable comparison between studies and settings, researchers and practitioners should be explicit about their choice of definition and measure. Using a cut-off of two or more conditions as part of the definition is widely adopted. Measure selection should be based on tools validated for the outcome being considered. Where there is no validated measure, or where multiple outcomes or populations are being considered, disease counts are appropriate.
| Original language | English |
|---|---|
| Pages (from-to) | 182-189 |
| Number of pages | 8 |
| Journal | European Journal of Public Health |
| Volume | 29 |
| Issue number | 1 |
| Early online date | 5 Jun 2018 |
| DOIs | |
| Publication status | Published - 1 Feb 2019 |
Bibliographical note
Funding: Dr Marjorie Johnston was funded by a Clinical Academic Fellowship from the Chief Scientist Office, Scotland (CAF/13/03), was affiliated with the Farr Institute of Health Informatics and Research Scotland and was an honorary Public Health Registrar at NHS Grampian.Keywords
- Journal Article
- DISEASES
- PRIMARY-CARE
- SOCIOECONOMIC DEPRIVATION
- PATTERNS
- HEALTH-CARE
- PREVALENCE
- QUALITY-OF-LIFE
- ADMINISTRATIVE DATABASES
- INTERVENTION
- COMORBIDITY
Access to Document
- Accepted Manuscript
This is a pre-copyedited, author-produced version of an article accepted for publication in European Journal of Public Health following peer review. The version of record Marjorie C Johnston, Michael Crilly, Corri Black, Gordon J Prescott, Stewart W Mercer; Defining and measuring multimorbidity: a systematic review of systematic reviews, European Journal of Public Health, Volume 29, Issue 1, 1 February 2019, Pages 182–189, is available online at: https://academic.oup.com/eurpub/article/29/1/182/5033670 website].