Development of the huntington disease work function scale

Bradley Brossman, Janet K Williams, Nancy Downing, James A Mills, Jane S Paulsen, PREDICT-HD Investigators And Coordinators Of The Huntington Study Group, Zosia Miedzybrodzka

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Objective: A work function measure specific for persons with prodromal Huntington disease (HD) was created to assist with workplace accommodations.

Methods: A self-report HD Work Function (HDWF) measure was developed from focus group and expert validation.

Results: Pilot studies with 238 people with prodromal HD, and 185 companions; and 89 people without prodromal HD, and 70 companions indicate that HDWF has acceptable internal consistency (Cronbach a = 0.77), acceptable interrater reliability (r = 0.58), and acceptable convergent validity with selected items from the Endicott Work Productivity Scale (r = -0.56), Social Adjustment Scale-Self Report (r = -0.29), and Everyday Cognition (r = -0.70). The HDWF can distinguish between people with prodromal HD and people with an HD family history who do not have prodromal HD (P < 0.0001).

Conclusions: The HDWF is a brief self-assessment that may be used to monitor work function.
Original languageEnglish
Pages (from-to)1300-1308
Number of pages9
JournalJournal of Occupational and Environmental Medicine
Issue number10
Publication statusPublished - Oct 2012


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