Draft whole genome sequences of the periodontal pathobionts Porphyromonas gingivalis, Prevotella intermedia and Tannerella forsythia contain phase variable restriction modification systems

Richard D. Haigh, Liam A. Crawford, Joseph D. Ralph, Joseph J. Wanford, Sonia R. Vartoukian, Karolin Hijazi, William Wade, Marco R. Oggioni

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)
33 Downloads (Pure)

Abstract

Periodontal disease comprises mild to severe inflammatory host responses to oral bacteria that can cause destruction of the tooth supporting tissue. We report genome sequences for eighteen clinical isolates of Porphyromonas gingivalis, Prevotella intermedia and Tannerella forsythia, Gram-negative obligate anaerobes that play a role in the periodontal disease process.
Original languageEnglish
Article numbere01229-17
Pages (from-to)1-3
Number of pages3
JournalGenome Announcements
Volume5
Issue number46
Early online date16 Nov 2017
DOIs
Publication statusPublished - Nov 2017

Bibliographical note

The periodontal strains used were collected during previous studies performed at the University of Cardiff (strains WW414, WW855 and WW2096), University of Bristol (WW2834, WW2842, WW2866, WW2881, WW28585, WW2903, WW2931, WW2952, WW3039, WW3040, and WW3102), King’s College London (WW5019, WW5127, and WW10960) and Queen Mary University of London (WW11663). Illumina sequencing was performed by the NUCLEUS Genomics Core Facility and data analysis used the Spectre2 and Alice2 High Performance Computing Facility at the University of Leicester. This work was in part funded by a grant from the BBSRC (BB/N002903/1) to MRO.

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