(E)-N-(3-(5-(3-Acetamidopropyl)-3,6-dioxopiperazin-2-yl)propyl)-5-hydroxy-3-methylpent-2-enamide

Gagan Preet; Rishi Vachaspathy Astakala; Joy Ebenezer Rajakulendran; Emmanuel T. Oluwabusola; Rainer Ebel; Marcel Jaspars

doi:10.3390/M1680

(E)-N-(3-(5-(3-Acetamidopropyl)-3,6-dioxopiperazin-2-yl)propyl)-5-hydroxy-3-methylpent-2-enamide

Gagan Preet^* (Corresponding Author), Rishi Vachaspathy Astakala^* (Corresponding Author), Joy Ebenezer Rajakulendran, Emmanuel T. Oluwabusola, Rainer Ebel, Marcel Jaspars

^*Corresponding author for this work

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Abstract

The Atacama Desert is an unexplored habitat with interesting possibilities for natural product chemistry due to the adaptations employed by microorganisms to survive the extreme salinity and high UV radiation present. Several soil samples were collected over the course of a few years in locations across the desert from which microorganisms were isolated. This paper reports on the isolation and structural characterisation, using LC-MS, and 1D and 2D NMR, of a new diketopiperazine that came from one of the fungi isolated from the Atacama Desert.

Original language	English
Article number	M1680
Journal	MolBank
Volume	2023
Issue number	3
DOIs	https://doi.org/10.3390/M1680
Publication status	Published - 1 Jul 2023

Bibliographical note

Funding
The collection of materials was carried out with financial support from the UK Newton Project for UK–Chile Collaboration (JIC CA 586) to Professor Mervyn Bibb, John Inness Centre, Norwich, UK.

Acknowledgments
The authors would like to thank Albrn Care India, Nidhan Singh Oberoi, and P.S. Oberoi, I.C.A.R-National Dairy Research Institute, India, as well as Aparna Koride for their continued support. They would also like to thank Russell Gray for his support in running the NMR experiments. Data collection was carried out in collaboration with Michael Goodfellow, University of Newcastle, and Juan Asenjo and Barbara Andrews, University of Chile.

Data Availability Statement

The spectroscopic data presented in this study are available as Supplementary Materials.

Keywords

diketopiperazine
fungal natural products
Atacama Desert
nuclear magnetic resonance
secondary metabolite
HR-ESI-LC-MS

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10.3390/M1680Licence: CC BY

Preet_etal_M_(E)-N-(3-(5-(3-Acetamidopropyl)_VOR
© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Final published version, 1.28 MBLicence: CC BY

Cite this

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title = "(E)-N-(3-(5-(3-Acetamidopropyl)-3,6-dioxopiperazin-2-yl)propyl)-5-hydroxy-3-methylpent-2-enamide",

abstract = "The Atacama Desert is an unexplored habitat with interesting possibilities for natural product chemistry due to the adaptations employed by microorganisms to survive the extreme salinity and high UV radiation present. Several soil samples were collected over the course of a few years in locations across the desert from which microorganisms were isolated. This paper reports on the isolation and structural characterisation, using LC-MS, and 1D and 2D NMR, of a new diketopiperazine that came from one of the fungi isolated from the Atacama Desert.",

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note = "Funding The collection of materials was carried out with financial support from the UK Newton Project for UK–Chile Collaboration (JIC CA 586) to Professor Mervyn Bibb, John Inness Centre, Norwich, UK. Acknowledgments The authors would like to thank Albrn Care India, Nidhan Singh Oberoi, and P.S. Oberoi, I.C.A.R-National Dairy Research Institute, India, as well as Aparna Koride for their continued support. They would also like to thank Russell Gray for his support in running the NMR experiments. Data collection was carried out in collaboration with Michael Goodfellow, University of Newcastle, and Juan Asenjo and Barbara Andrews, University of Chile.",

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AU - Preet, Gagan

AU - Astakala, Rishi Vachaspathy

AU - Rajakulendran, Joy Ebenezer

AU - Oluwabusola, Emmanuel T.

AU - Ebel, Rainer

AU - Jaspars, Marcel

N1 - Funding The collection of materials was carried out with financial support from the UK Newton Project for UK–Chile Collaboration (JIC CA 586) to Professor Mervyn Bibb, John Inness Centre, Norwich, UK. Acknowledgments The authors would like to thank Albrn Care India, Nidhan Singh Oberoi, and P.S. Oberoi, I.C.A.R-National Dairy Research Institute, India, as well as Aparna Koride for their continued support. They would also like to thank Russell Gray for his support in running the NMR experiments. Data collection was carried out in collaboration with Michael Goodfellow, University of Newcastle, and Juan Asenjo and Barbara Andrews, University of Chile.

PY - 2023/7/1

Y1 - 2023/7/1

N2 - The Atacama Desert is an unexplored habitat with interesting possibilities for natural product chemistry due to the adaptations employed by microorganisms to survive the extreme salinity and high UV radiation present. Several soil samples were collected over the course of a few years in locations across the desert from which microorganisms were isolated. This paper reports on the isolation and structural characterisation, using LC-MS, and 1D and 2D NMR, of a new diketopiperazine that came from one of the fungi isolated from the Atacama Desert.

AB - The Atacama Desert is an unexplored habitat with interesting possibilities for natural product chemistry due to the adaptations employed by microorganisms to survive the extreme salinity and high UV radiation present. Several soil samples were collected over the course of a few years in locations across the desert from which microorganisms were isolated. This paper reports on the isolation and structural characterisation, using LC-MS, and 1D and 2D NMR, of a new diketopiperazine that came from one of the fungi isolated from the Atacama Desert.

KW - diketopiperazine

KW - fungal natural products

KW - Atacama Desert

KW - nuclear magnetic resonance

KW - secondary metabolite

KW - HR-ESI-LC-MS

UR - https://doi.org/10.3390/M1680

U2 - 10.3390/M1680

DO - 10.3390/M1680

M3 - Article

SN - 1422-8599

VL - 2023

JO - MolBank

JF - MolBank

IS - 3

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ER -

(E)-N-(3-(5-(3-Acetamidopropyl)-3,6-dioxopiperazin-2-yl)propyl)-5-hydroxy-3-methylpent-2-enamide

Abstract

Bibliographical note

Data Availability Statement

Keywords

Access to Document

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