Abstract
Regular exercise and physical activity are a cornerstone of the prevention and treatment of widespread cardiometabolic diseases such as obesity, type 2 diabetes (T2D), and cardiovascular diseases. On a cellular and molecular level, virtually all processes dysregulated in disease and involved in the response and adaptation of the body to exercise training are downstream of tissue biological clocks and their alignment within the body (1). This circadian regulation that allows our bodies to adapt to the changes of day and night in the span of 24 hours modulates energy metabolism, cell repair and renewal, and even immunological processes (2). Therefore, it is clear that time-of-day is an important factor in maximizing the health benefits of exercise and physical activity for disease prevention and treatment...
Original language | English |
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Article number | 1180851 |
Number of pages | 3 |
Journal | Frontiers in Endocrinology |
Volume | 14 |
Early online date | 21 Mar 2023 |
DOIs | |
Publication status | Published - 21 Mar 2023 |
Bibliographical note
AcknowledgmentsWe would like to thank all authors and reviewers who contributed to this collection.
Keywords
- circadian rhythms
- physical activity
- exercise
- skeletal muscle
- metabolic health