Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma

D McAteer; Fintan Wallis; G Couper; Murdoch Norton; Andrew Welch; Duff Bruce; Ken Park; Marianne Nicholson; Fiona Jane Gilbert; Peter Frederick Sharp

Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma

D McAteer, Fintan Wallis, G Couper, Murdoch Norton, Andrew Welch, Duff Bruce, Ken Park, Marianne Nicholson, Fiona Jane Gilbert, Peter Frederick Sharp

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Abstract

The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging.

Original language	English
Pages (from-to)	525-529
Number of pages	5
Journal	British Journal of Radiology
Volume	72
Issue number	858
Publication status	Published - Jun 1999

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title = "Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma",

abstract = "The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging. ",

author = "D McAteer and Fintan Wallis and G Couper and Murdoch Norton and Andrew Welch and Duff Bruce and Ken Park and Marianne Nicholson and Gilbert, {Fiona Jane} and Sharp, {Peter Frederick}",

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language = "English",

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T1 - Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma

AU - McAteer, D

AU - Wallis, Fintan

AU - Couper, G

AU - Norton, Murdoch

AU - Welch, Andrew

AU - Bruce, Duff

AU - Park, Ken

AU - Nicholson, Marianne

AU - Gilbert, Fiona Jane

AU - Sharp, Peter Frederick

PY - 1999/6

Y1 - 1999/6

N2 - The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging.

AB - The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging.

M3 - Article

SN - 0007-1285

VL - 72

SP - 525

EP - 529

JO - British Journal of Radiology

JF - British Journal of Radiology

IS - 858

ER -

Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma

Abstract

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