Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis

Boni A Afouda; Adam T Lynch; Eduardo De Paiva Alves; Stefan Hoppler

doi:10.1016/j.dib.2018.01.005

Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis

Boni A Afouda, Adam T Lynch, Eduardo De Paiva Alves, Stefan Hoppler^* (Corresponding Author)

^*Corresponding author for this work

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Abstract

The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (B.A. Afouda, A.T. Lynch, E. de Paiva Alves, S. Hoppler, 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.

Original language	English
Pages (from-to)	559-563
Number of pages	5
Journal	Data in brief
Volume	17
Early online date	17 Jan 2018
DOIs	https://doi.org/10.1016/j.dib.2018.01.005
Publication status	Published - Apr 2018

Bibliographical note

Funding sources
This work was supported by British Heart Foundation (BHF Project Grant no PG/13/23/30080 to B.A.A and S.H.), Biotechnology and Biological Sciences Research Council (BB/M001695/1 to S.H.) and the University of Aberdeen (for A.T.L).

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Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
c2018 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Final published version, 204 KBLicence: CC BY

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Cite this

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title = "Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis",

abstract = "The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (B.A. Afouda, A.T. Lynch, E. de Paiva Alves, S. Hoppler, 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.",

author = "Afouda, {Boni A} and Lynch, {Adam T} and {De Paiva Alves}, Eduardo and Stefan Hoppler",

note = "Funding sources This work was supported by British Heart Foundation (BHF Project Grant no PG/13/23/30080 to B.A.A and S.H.), Biotechnology and Biological Sciences Research Council (BB/M001695/1 to S.H.) and the University of Aberdeen (for A.T.L).",

year = "2018",

month = apr,

doi = "10.1016/j.dib.2018.01.005",

language = "English",

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journal = "Data in brief",

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AU - Afouda, Boni A

AU - Lynch, Adam T

AU - De Paiva Alves, Eduardo

AU - Hoppler, Stefan

N1 - Funding sources This work was supported by British Heart Foundation (BHF Project Grant no PG/13/23/30080 to B.A.A and S.H.), Biotechnology and Biological Sciences Research Council (BB/M001695/1 to S.H.) and the University of Aberdeen (for A.T.L).

PY - 2018/4

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N2 - The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (B.A. Afouda, A.T. Lynch, E. de Paiva Alves, S. Hoppler, 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.

AB - The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (B.A. Afouda, A.T. Lynch, E. de Paiva Alves, S. Hoppler, 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.

U2 - 10.1016/j.dib.2018.01.005

DO - 10.1016/j.dib.2018.01.005

M3 - Article

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VL - 17

SP - 559

EP - 563

JO - Data in brief

JF - Data in brief

ER -

Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis

Abstract

Bibliographical note

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