The mitral valve is a complex anatomical structure whose physiological functioning relies on the biomechanical properties and structural integrity of its components. Their compromise can lead to mitral valve dysfunction, associated with morbidity and mortality. Therefore, a review on the morphometry of the mitral valve is crucial, more specifically on the importance of valve dimensions and shape for its function. This review initially provides a brief background on the anatomy and physiology of the mitral valve, followed by an analysis of the morphological information available. A characterisation of mathematical descriptions of several parts of the valve is performed and the impact of different dimensions and shape changes in disease is then outlined. Finally, a section regarding future directions and recommendations for the use of morphometric information in clinical analysis of the mitral valve is presented.
Bibliographical noteFunding information:
The creation of the database employed in our study was sponsored by the University of Aberdeen, under the research study ‘Exercise Capacity in Adults’.
- computational anatomy
- mitral valve
- mitral valve disease
- morphology analysis
- ANNULAR GEOMETRY
- TRANSESOPHAGEAL ECHOCARDIOGRAPHY
- LEAFLET 2ND-ORDER CHORDAE
- DYNAMIC DEFORMATION
- MECHANISTIC INSIGHTS