Greenhouse Gas Emissions from Respiratory Treatments: Results from the SABA CARBON International Study

Ashraf Alzaabi, John P. Bell, Felicia Montero-Arias, David B. Price, David J. Jackson, Hao-Chien Wang, Nigel Budgen, Hisham Farouk, Ekaterina Maslova

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Abstract

Healthcare systems are looking to reduce their carbon impact. Short-acting β2-agonist (SABA) overuse (≥ 3 canisters/year) is common in asthma and linked to poor outcomes; however, its environmental impact remains unknown. As part of the CARBON programme, this study retrospectively quantified the carbon footprint of SABA and controller inhalers across all respiratory indications and SABA overuse in asthma in lower-middle-income countries (LMICs), upper-middle-income countries and high-income countries across Africa, Asia Pacific, Latin America and the Middle East.
Original languageEnglish
Pages (from-to)4836-4856
Number of pages21
JournalAdvances in Therapy
Volume40
Issue number11
Early online date9 Sept 2023
DOIs
Publication statusPublished - Nov 2023

Bibliographical note

Acknowledgements
Medical Writing, Editorial, and Other Assistance
Medical writing and editorial support were provided by Tejaswini Subbannayya, PhD, of Cactus Life Sciences (part of Cactus Communications, Mumbai, India), in accordance with Good Publication Practice (GPP3) guidelines (http://www.ismpp.org/gpp3). This support was fully funded by AstraZeneca.

Funding
AstraZeneca funded the study; was involved in the study design, protocol development, study conduct and statistical analysis; and was given the opportunity to review the manuscript before submission. AstraZeneca also funded medical writing support and the development of the graphical abstract. AstraZeneca funded the journal’s Rapid Service and Open Access fees.

Data Availability Statement

Data underlying the SABINA III findings described in this manuscript may be obtained in accordance with AstraZeneca’s data sharing policy described at https://astrazenecagrouptrials.pharmacm.com/ST/Submission/Disclosure. Data for clinical research studies directly listed on Vivli can be requested through Vivli at www.vivli.org. Data for clinical research studies not listed on Vivli could be requested through Vivli at https://vivli.org/members/enquiries-about-studies-not-listed-on-the-vivli-platform/. AstraZeneca Vivli member page is also available outlining further details: https://vivli.org/ourmember/astrazeneca/.

Keywords

  • Asthma
  • Asthma control
  • carbon footprint
  • Environmental monitoring
  • Greenhouse gas emissions
  • Inhalers
  • Inhaler therapies
  • SABA
  • Short-acting β2-agonist

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