Harpulliasides A and B: Two new benzeneacetic acid derivatives from Harpullia pendula

Mohamed Salaheldin A. Abdelkader; Mostafa Rateb; Gamal A. Mohamed; Marcel Jaspars

doi:10.1016/j.phytol.2015.12.006

Harpulliasides A and B: Two new benzeneacetic acid derivatives from Harpullia pendula

Mohamed Salaheldin A. Abdelkader^*, Mostafa Rateb, Gamal A. Mohamed, Marcel Jaspars

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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Abstract

Two new benzeneacetic acid derivatives, harpulliaside A (1) and harpulliaside B (2), together with five known flavonoid glycosides; quercetin-3-O-beta-D-glucoside (3), kaempferol-3-O-beta-D-glucoside (4), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-rhamnopyranoside (5), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 4)-alpha-L-rhamnopyranoside (6), and kaempferol-3-O-beta-D-apiofuranosyl-(1 -> 2)-beta-D-glucopyranoside (7) were isolated and characterized for the first time from the leaves of Harpullia pendula. The structures of these compounds were established by 1D and 2D NMR experiments and HRESIMS analyses. The new compounds were assessed for their antibacterial effect against different Gram-positive and Gram negative bacterial strains. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	131-135
Number of pages	5
Journal	Phytochemistry letters
Volume	15
Early online date	11 Dec 2015
DOIs	https://doi.org/10.1016/j.phytol.2015.12.006
Publication status	Published - Mar 2016

Keywords

harpullia pendula
sapindaceae
benzeneacetic acid derivatives
harpulliasides A and B
flavonoid glycosides
antibacterial
sophora-flavescens
flavonol glycosides
chemical constituents
cupanioides
saponins
NMR

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@article{dc79f596fc3f450488288c885e15e52b,

title = "Harpulliasides A and B: Two new benzeneacetic acid derivatives from Harpullia pendula",

abstract = "Two new benzeneacetic acid derivatives, harpulliaside A (1) and harpulliaside B (2), together with five known flavonoid glycosides; quercetin-3-O-beta-D-glucoside (3), kaempferol-3-O-beta-D-glucoside (4), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-rhamnopyranoside (5), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 4)-alpha-L-rhamnopyranoside (6), and kaempferol-3-O-beta-D-apiofuranosyl-(1 -> 2)-beta-D-glucopyranoside (7) were isolated and characterized for the first time from the leaves of Harpullia pendula. The structures of these compounds were established by 1D and 2D NMR experiments and HRESIMS analyses. The new compounds were assessed for their antibacterial effect against different Gram-positive and Gram negative bacterial strains. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.",

keywords = "harpullia pendula, sapindaceae, benzeneacetic acid derivatives, harpulliasides A and B, flavonoid glycosides, antibacterial, sophora-flavescens, flavonol glycosides, chemical constituents, cupanioides, saponins, NMR",

author = "Abdelkader, {Mohamed Salaheldin A.} and Mostafa Rateb and Mohamed, {Gamal A.} and Marcel Jaspars",

year = "2016",

month = mar,

doi = "10.1016/j.phytol.2015.12.006",

language = "English",

volume = "15",

pages = "131--135",

journal = "Phytochemistry letters",

issn = "1874-3900",

publisher = "ELSEVIER SCIENCE BV",

}

TY - JOUR

T1 - Harpulliasides A and B

T2 - Two new benzeneacetic acid derivatives from Harpullia pendula

AU - Abdelkader, Mohamed Salaheldin A.

AU - Rateb, Mostafa

AU - Mohamed, Gamal A.

AU - Jaspars, Marcel

PY - 2016/3

Y1 - 2016/3

N2 - Two new benzeneacetic acid derivatives, harpulliaside A (1) and harpulliaside B (2), together with five known flavonoid glycosides; quercetin-3-O-beta-D-glucoside (3), kaempferol-3-O-beta-D-glucoside (4), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-rhamnopyranoside (5), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 4)-alpha-L-rhamnopyranoside (6), and kaempferol-3-O-beta-D-apiofuranosyl-(1 -> 2)-beta-D-glucopyranoside (7) were isolated and characterized for the first time from the leaves of Harpullia pendula. The structures of these compounds were established by 1D and 2D NMR experiments and HRESIMS analyses. The new compounds were assessed for their antibacterial effect against different Gram-positive and Gram negative bacterial strains. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

AB - Two new benzeneacetic acid derivatives, harpulliaside A (1) and harpulliaside B (2), together with five known flavonoid glycosides; quercetin-3-O-beta-D-glucoside (3), kaempferol-3-O-beta-D-glucoside (4), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 2)-alpha-L-rhamnopyranoside (5), kaempferol-3-O-beta-D-glucopyranosyl-(1 -> 4)-alpha-L-rhamnopyranoside (6), and kaempferol-3-O-beta-D-apiofuranosyl-(1 -> 2)-beta-D-glucopyranoside (7) were isolated and characterized for the first time from the leaves of Harpullia pendula. The structures of these compounds were established by 1D and 2D NMR experiments and HRESIMS analyses. The new compounds were assessed for their antibacterial effect against different Gram-positive and Gram negative bacterial strains. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

KW - harpullia pendula

KW - sapindaceae

KW - benzeneacetic acid derivatives

KW - harpulliasides A and B

KW - flavonoid glycosides

KW - antibacterial

KW - sophora-flavescens

KW - flavonol glycosides

KW - chemical constituents

KW - cupanioides

KW - saponins

KW - NMR

U2 - 10.1016/j.phytol.2015.12.006

DO - 10.1016/j.phytol.2015.12.006

M3 - Article

SN - 1874-3900

VL - 15

SP - 131

EP - 135

JO - Phytochemistry letters

JF - Phytochemistry letters

ER -

Harpulliasides A and B: Two new benzeneacetic acid derivatives from Harpullia pendula

Abstract

Keywords

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