Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar

Harinirina Aina Rabemananjara, Vololoniaina Raharinosy, Ravo Michèle Razafimahefa, Jean Pierre Ravalohery, Jean Théophile Rafisandratantsoa, Soa Fy Andriamandimby, Minoarisoa Rajerison, Soanandrasana Rahelinirina, Aina Harimanana, Judickaelle Irinantenaina, Marie Marie Olive, Christophe Rogier, Noël Tordo, Rainer G. Ulrich, Jean Marc Reynes, Stéphane Petres, Jean Michel Heraud, Sandra Telfer* (Corresponding Author), Claudia Filippone* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)
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We conducted a national human serologic study of a hantavirus detected in Madagascar rodents using a commercial kit and a new ELISA targeting the virus. Our results suggest a conservative estimate of 2.7% (46/1,680) IgG seroprevalence. A second single-district study using the new ELISA revealed a higher prevalence (7.2%; 10/139).

Original languageEnglish
Pages (from-to)587-590
Number of pages4
JournalEmerging Infectious Diseases
Issue number3
Early online date19 Feb 2020
Publication statusPublished - Mar 2020

Bibliographical note

We thank all colleagues from the Virology, Plague and
Epidemiology Units of the Institut Pasteur de Madagascar
who aided with field and laboratory work. We thank
Corinne Jallet for help with some ELISA assays and Rasa
Petraityte-Burneikiene and Aurelija Zvirbliene for providing
antigen for additional analysis. We thank Reagena for
constructive exchanges during provision of the kits.
This work was supported by Wellcome Trust Fellowships
(no. 081705 and 095171 to S.T.) and Institut Pasteur de
Madagascar, and by PTR (Progamme Transversal de
Recherche) HANTAREV at Institut Pasteur, Paris.


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