Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary


Immunodeficiency, both primary and secondary, can occur due to a variety of defects within the immune system. Clinical manifestation is heterogeneous, with infective, immune-mediated, malignant and auto-immune conditions occurring depending on the area of immune system affected. The gastro-intestinal tract is frequently affected. Here we discuss important subtypes of immunodeficiency and gastrointestinal presentations associated with these.
Original languageEnglish
Title of host publicationEncyclopedia of Gastroenterology
EditorsErnst Kuipers
ISBN (Electronic)9780128187289
Publication statusPublished - 6 Nov 2019

Bibliographical note

Encyclopedia of Gastroenterology, Second Edition provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included.


  • Antibody deficiency
  • B cell
  • diarrhea
  • human immunodeficiency virus
  • infective complication
  • primary immune deficiency
  • secondary immune deficiency
  • T cell
  • villous atrophy


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