Immunology of Gut-Bone Signaling

Fraser L Collins; Jonathan D Schepper; Naiomy Deliz Rios-Arce; Michael D Steury; Ho Jun Kang; Heather Mallin; Daniel Schoenherr; Glen Camfield; Saima Chishti; Laura R McCabe; Narayanan Parameswaran

doi:10.1007/978-3-319-66653-2_5

Immunology of Gut-Bone Signaling

Fraser L Collins, Jonathan D Schepper, Naiomy Deliz Rios-Arce, Michael D Steury, Ho Jun Kang, Heather Mallin, Daniel Schoenherr, Glen Camfield, Saima Chishti, Laura R McCabe, Narayanan Parameswaran

Applied Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

17 Citations (Scopus)

Abstract

In recent years a link between the gastrointestinal tract and bone health has started to gain significant attention. Dysbiosis of the intestinal microbiota has been linked to the pathology of a number of diseases which are associated with bone loss. In addition modulation of the intestinal microbiota with probiotic bacteria has revealed to have both beneficial local and systemic effects. In the present chapter, we discuss the intestinal and bone immune systems, explore how intestinal disease affects the immune system, and examine how these pathologic changes could adversely impact bone health.

Original language	English
Title of host publication	Understanding the Gut-Bone Signaling Axis
Subtitle of host publication	Mechanisms and Therapeutic Implications
Editors	Laura R McCabe, Narayanan Parameswaran
Place of Publication	Cham
Publisher	Springer
Pages	59-94
Number of pages	36
ISBN (Electronic)	978-3-319-66653-2
ISBN (Print)	978-3-319-66651-8
DOIs	https://doi.org/10.1007/978-3-319-66653-2_5
Publication status	Published - 2017

Publication series

Name	Advances in Experimental Medicine and Biology
Publisher	Springer New York
Volume	1033
ISSN (Print)	0065-2598
ISSN (Electronic)	2214-8019

Keywords

Animals
Bone Remodeling/immunology
Bone and Bones/cytology
Cytokines/immunology
Gastrointestinal Tract/cytology
Humans
Immune System/cytology
Intestinal Diseases/immunology
Lymphocytes/immunology
Signal Transduction/immunology

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Collins, F. L., Schepper, J. D., Rios-Arce, N. D., Steury, M. D., Kang, H. J., Mallin, H., Schoenherr, D., Camfield, G., Chishti, S., McCabe, L. R., & Parameswaran, N. (2017). Immunology of Gut-Bone Signaling. In L. R. McCabe, & N. Parameswaran (Eds.), Understanding the Gut-Bone Signaling Axis: Mechanisms and Therapeutic Implications (pp. 59-94). (Advances in Experimental Medicine and Biology; Vol. 1033). Springer . https://doi.org/10.1007/978-3-319-66653-2_5

Immunology of Gut-Bone Signaling. / Collins, Fraser L; Schepper, Jonathan D; Rios-Arce, Naiomy Deliz et al.
Understanding the Gut-Bone Signaling Axis: Mechanisms and Therapeutic Implications. ed. / Laura R McCabe; Narayanan Parameswaran. Cham: Springer , 2017. p. 59-94 (Advances in Experimental Medicine and Biology; Vol. 1033).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Collins, FL, Schepper, JD, Rios-Arce, ND, Steury, MD, Kang, HJ, Mallin, H, Schoenherr, D, Camfield, G, Chishti, S, McCabe, LR & Parameswaran, N 2017, Immunology of Gut-Bone Signaling. in LR McCabe & N Parameswaran (eds), Understanding the Gut-Bone Signaling Axis: Mechanisms and Therapeutic Implications. Advances in Experimental Medicine and Biology, vol. 1033, Springer , Cham, pp. 59-94. https://doi.org/10.1007/978-3-319-66653-2_5

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KW - Cytokines/immunology

KW - Gastrointestinal Tract/cytology

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KW - Immune System/cytology

KW - Intestinal Diseases/immunology

KW - Lymphocytes/immunology

KW - Signal Transduction/immunology

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Immunology of Gut-Bone Signaling

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Keywords

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