Inactivation of anandamide signaling: A continuing Debate

H. Khairy; Wael E Houssen

doi:10.3390/ph3113355

Inactivation of anandamide signaling: A continuing Debate

H. Khairy, Wael E Houssen

Medical Sciences

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Abstract

Since the first endocannabinoid anandamide was identified in 1992, extensive research has been conducted to characterize the elements of the tightly controlled endocannabinoid signaling system. While it was established that the activity of endocannabinoids are terminated by a two-step process that includes cellular uptake and degradation, there is still a continuing debate about the mechanistic role of these rocesses in inactivating anandamide signals.

Original language	English
Pages (from-to)	3355-3370
Number of pages	16
Journal	Pharmaceuticals
Volume	3
Issue number	11
DOIs	https://doi.org/10.3390/ph3113355
Publication status	Published - 1 Jan 2010

Keywords

endocannabinoid inactivation
anandamide
ethanolamine

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10.3390/ph3113355

Pharmaceuticals
Khairy, H & Houssen, WE 2010, 'Inactivation of anandamide signaling: A continuing Debate' Pharmaceuticals, vol 3, no. 11, pp. 3355-3370.
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Inactivation of anandamide signaling: A continuing Debate

Abstract

Keywords

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