TY - JOUR
T1 - Individualizing the risk for preterm birth
T2 - An overview of the literature
AU - Van os, Melanie
AU - Van Der Ven, Jeanine
AU - Kazemier, Brenda
AU - Haak, Monique
AU - Pajkrt, Eva
AU - Mol, Ben W.
AU - de Groot, Christianne
PY - 2013/9/1
Y1 - 2013/9/1
N2 - Preterm birth is the most important cause of perinatal morbidity and mortality worldwide, and ranks among the top 10 of global causes of burden of disease. Since treatment of threatened preterm delivery has limited effectiveness, the focus is on primary and secondary prevention. Identification of risk indicators in early pregnancy provides the opportunity for preventive measures. To determine the potential impact of individualized risk indicators on the prediction of preterm birth, we reviewed the literature on this topic. Risk indicators for spontaneous preterm birth can be categorized in five groups; characteristics of the individual (ethnicity/race), characteristics of the fetus (fetal gender fetal number and chorionicity), obstetric history (history of preterm birth), modifiable risk indicators (social status, life style, infection) and signs of early labour; potential predictors (sonographic markers, biomarkes). Risk for preterm birth can be seen as a continuous transition from one state to the other. The number of studies that integrate these data is limited.
AB - Preterm birth is the most important cause of perinatal morbidity and mortality worldwide, and ranks among the top 10 of global causes of burden of disease. Since treatment of threatened preterm delivery has limited effectiveness, the focus is on primary and secondary prevention. Identification of risk indicators in early pregnancy provides the opportunity for preventive measures. To determine the potential impact of individualized risk indicators on the prediction of preterm birth, we reviewed the literature on this topic. Risk indicators for spontaneous preterm birth can be categorized in five groups; characteristics of the individual (ethnicity/race), characteristics of the fetus (fetal gender fetal number and chorionicity), obstetric history (history of preterm birth), modifiable risk indicators (social status, life style, infection) and signs of early labour; potential predictors (sonographic markers, biomarkes). Risk for preterm birth can be seen as a continuous transition from one state to the other. The number of studies that integrate these data is limited.
KW - cervical length
KW - ethnicity
KW - fetal fibronectin
KW - history of preterm birth
KW - prediction models
KW - preterm birth
KW - risk indicators
KW - singleton pregnancy
KW - socio-economic indicators
UR - http://www.scopus.com/inward/record.url?scp=85027916516&partnerID=8YFLogxK
U2 - 10.1586/17474108.2013.825481
DO - 10.1586/17474108.2013.825481
M3 - Review article
AN - SCOPUS:85027916516
SN - 1747-4108
VL - 8
SP - 435
EP - 442
JO - Expert Review of Obstetrics and Gynecology
JF - Expert Review of Obstetrics and Gynecology
IS - 5
ER -