Abstract
The mitogen-activated protein (MAP) kinase pathways have been highlighted as a possible link between exercise and adaptive changes in skeletal muscle. In this study, the effect of exercise intensity on the activation of the ERK/MAP kinase pathway was investigated in human skeletal muscle. One-leg exercise at low (40% maximal oxygen consumption, VO2max for 30 min) and high (75% VO2max for 30 min) intensity resulted in 11.5+8. I-fold and 39.7+/-6.3-fold (mean +/-SEM) increases in ERK1/2 phosphorylation (P
Original language | English |
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Pages (from-to) | 317-22 |
Number of pages | 6 |
Journal | Pflugers Archiv : European Journal of Physiology |
Volume | 441 |
Issue number | 2-3 |
DOIs | |
Publication status | Published - 1 Dec 2000 |
Keywords
- Adult
- Cyclic AMP Response Element-Binding Protein
- Exercise
- Female
- Freeze Drying
- Humans
- Male
- Mitogen-Activated Protein Kinase 1
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases
- Muscle, Skeletal
- Oxygen Consumption
- Phosphorylation
- Signal Transduction