Innate barriers to viral infection

Blossom Damania*, David J. Blackbourn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Innate immunity represents the foremost barrier to viral infection. In order to infect a cell efficiently, viruses need to evade innate immune effectors such as interferons and inflammatory cytokines. Pattern recognition receptors can detect viral components or pathogen-associated molecular patterns. These receptors then elicit innate immune responses that result in the generation of type I interferons and proinflammatory cytokines. Organized by the Society for General Microbiology, one session of this conference focused on the current state-of-the-art knowledge on innate barriers to infection of different RNA and DNA viruses. Experts working on innate immunity in the context of viral infection provided insight into different aspects of innate immune recognition and also discussed areas for future research. Here, we provide an overview of the session on innate barriers to infection.

Original languageEnglish
Pages (from-to)815-822
Number of pages8
JournalFuture Microbiology
Issue number7
Publication statusPublished - Jul 2012


  • DNA virus
  • inflammatory cytokine
  • innate immunity
  • interferon
  • RNA virus


Dive into the research topics of 'Innate barriers to viral infection'. Together they form a unique fingerprint.

Cite this