Long-term colorectal-cancer incidence and mortality after lower endoscopy

Reiko Nishihara, Kana Wu, Paul Lochhead, Teppei Morikawa, Xiaoyun Liao, Zhi Rong Qian, Kentaro Inamura, Sun A Kim, Aya Kuchiba, Mai Yamauchi, Yu Imamura, Walter C Willett, Bernard A Rosner, Charles S Fuchs, Edward Giovannucci, Shuji Ogino, Andrew T Chan

Research output: Contribution to journalArticlepeer-review

1087 Citations (Scopus)


Colonoscopy and sigmoidoscopy provide protection against colorectal cancer, but the magnitude and duration of protection, particularly against cancer of the proximal colon, remain uncertain.
Original languageEnglish
Pages (from-to)1095-1105
Number of pages11
JournalThe New England Journal of Medicine
Issue number12
Publication statusPublished - 19 Sept 2013


  • Adenoma
  • Aged
  • Cohort Studies
  • Colonic Polyps
  • Colonoscopy
  • Colorectal Neoplasms
  • DNA, Neoplasm
  • Early Detection of Cancer
  • Female
  • Humans
  • Incidence
  • Male
  • Microsatellite Instability
  • Middle Aged
  • Multivariate Analysis
  • Mutation
  • Sigmoidoscopy
  • United States


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