Lorlatinib for previously treated ALK-positive advanced non-small-cell lung cancer

Clare Robertson, Shona Fielding, Andrew Walker, Daniel Kopasker, Thenmalar Vadiveloo, Paul Manson, Gillian Price, Miriam Brazzelli, Graham Scotland

Research output: Book/ReportCommissioned Report

Abstract

Lorlatinib is recommended, within its marketing authorisation, as an option for treating anaplastic lymphoma kinase (ALK)-positive advanced non-small-cell lung cancer (NSCLC) in adults whose disease has progressed after:

- alectinib or ceritinib as the first ALK tyrosine kinase inhibitor or

- crizotinib and at least 1 other ALK tyrosine kinase inhibitor.

It is recommended only if the company provides lorlatinib according to the commercial arrangement.
Original languageEnglish
PublisherEvidence Review Group report in support of NICE STA Programme. London: National Institute for Health and Care Excellence
Commissioning bodyNational Institute for Health and Care Excellence
Publication statusPublished - 2019

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