Abstract
Chronic kidney disease is characterized by progressive interstitial fibrosis, reduced blood flow, and tubular atrophy, which present a common pathway of destruction irrespective of the initial underlying pathology. There is comprehensive evidence that the interactions of infiltrating macrophages with resident tissue cells play a critical role in this process. A new study now describes the correlation between macrophages, capillary density, and interstitial scarring and suggests distinct differences in early and advanced renal disease.
Original language | English |
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Pages (from-to) | 405-406 |
Number of pages | 2 |
Journal | Kidney International |
Volume | 74 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2 Aug 2008 |