Macrophages and hypoxia in human chronic kidney disease

Lars-Peter Erwig

Research output: Contribution to journalEditorial

11 Citations (Scopus)


Chronic kidney disease is characterized by progressive interstitial fibrosis, reduced blood flow, and tubular atrophy, which present a common pathway of destruction irrespective of the initial underlying pathology. There is comprehensive evidence that the interactions of infiltrating macrophages with resident tissue cells play a critical role in this process. A new study now describes the correlation between macrophages, capillary density, and interstitial scarring and suggests distinct differences in early and advanced renal disease.

Original languageEnglish
Pages (from-to)405-406
Number of pages2
JournalKidney International
Issue number4
Publication statusPublished - 2 Aug 2008


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