Marine natural products from the deep Pacific as potential non-linear optical chromophores

Bruce F. Milne, Patrick Norman, Fernando Nogueira, Cláudia Cardoso

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Theoretical analysis using quadratic response theory within the time-dependent density functional theory (TDDFT) formalism shows that the dermacozines, a group of phenazine-based compounds isolated from cultures of Dermacoccus abyssi found in the Mariana Trench, possess large first hyperpolarisability (β) values at common incident laser wavelengths that are highly sensitive to the degree and type of substitution of the core structure. The phenazine moiety is a versatile and tunable chromophore for non-linear optics and this work serves to highlight the potential that (marine) natural products, even those found in the darkest places on the planet, may have for aiding developments in optical materials design.
Original languageEnglish
Pages (from-to)14814-14822
Number of pages9
JournalPhysical Chemistry Chemical Physics
Issue number35
Publication statusPublished - 24 Jul 2013

Bibliographical note

BFM, FN and CC thank the Portuguese Foundation for Science and Technology for funding (PTDC/FIS/103587/2008) and the Laboratory for Advanced Computation of the University of Coimbra for the provision of computer resources, technical support and assistance. PN acknowledges financial support from the Swedish Research Council (Grant No. 621-2010-5014).


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