Abstract
Intake of fish, fish oil, and long-chain n-3 polyunsaturated fatty acids may help to prevent the development of chronic diseases such as coronary heart disease and cancer. Their anti-inflammatory properties are believed to play an important role in this beneficial effect. Long-chain n-3 polyunsaturated fatty acids modulate endothelial activation, eicosanoid metabolism (including epoxygenation pathways), and inflammatory resolution in vitro. Future studies should aim to elucidate novel biomarkers that can be applied to measure the efficacy of long-chain n-3 polyunsaturated fatty acids in relation to inflammation in vivo.
Original language | English |
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Title of host publication | Bioactive Food as Interventions for Arthritis and Related Inflammatory Diseases |
Editors | Ronald Ross Watson, Victor R. Preedy |
Publisher | Elsevier Inc |
Pages | 545-553 |
Number of pages | 9 |
ISBN (Print) | 9780123971562 |
DOIs | |
Publication status | Published - 2013 |
Keywords
- Biomarkers
- Cancer
- Cardiovascular disease
- Eicosanoid metabolism
- Endothelial activation
- Fish
- Fish oil
- Inflammation
- Inflammatory resolution
- Long-chain n-3 polyunsaturated fatty acids