Miosis during L-Dopa Therapy

A. S.D. Spiers, D. B. Calne, P. M. Fayers

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


The pupillary diameter of 11 patients with Parkinson's disease was significantly decreased four hours after ingestion of L-dopa. It is suggested that this miosis may be caused by diminished noradrenaline output at sympathetic nerve endings, or alternatively by an action on the central nervous system.

Original languageEnglish
Pages (from-to)639-640
Number of pages2
JournalBritish Medical Journal
Issue number5710
Publication statusPublished - 13 Jun 1970


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