MiR-492 as an important biomarker for early diagnosis and targeted treatment in different cancers

Eskandar Taghizadeh; Forough Taheri; Daryoush Rostami; Pedram G. Renani; Gordon A. Ferns; Alireza Pasdar; Majid G. Mobarhan

doi:10.2174/1573394716666200309124048

MiR-492 as an important biomarker for early diagnosis and targeted treatment in different cancers

Eskandar Taghizadeh, Forough Taheri, Daryoush Rostami, Pedram G. Renani, Gordon A. Ferns, Alireza Pasdar^* (Corresponding Author), Majid G. Mobarhan^* (Corresponding Author)

^*Corresponding author for this work

Applied Medicine

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Abstract

Recent studies have led to a more detailed understanding of the roles played by microRNAs in health and disease, and their potential use as biomarkers in physiological and pathophysiological processes involving cancer initiation and progression. MiR-492 is encoded by a pseudogene, has a key role in some human cancer cells and its overexpression in tissues, and it has been proposed that it can be used as a good biomarker for management and early diagnosis of some cancers including breast cancer, colorectal and ovarian cancer, hepatocellular cancer, retinoblastoma and pancreatic cancer. The aim of this review was to summarize the data of MiR-492 for early diagnosis and treatment of some types of related cancers.

Original language	English
Pages (from-to)	269-275
Number of pages	7
Journal	Current Cancer Therapy Reviews
Volume	16
Issue number	4
Early online date	20 Nov 2020
DOIs	https://doi.org/10.2174/1573394716666200309124048
Publication status	Published - 20 Nov 2020

Keywords

Biomarker
Breast cancer
Colorectal cancer
MicroRNAs
MiR-492
RNA-silencing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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abstract = "Recent studies have led to a more detailed understanding of the roles played by microRNAs in health and disease, and their potential use as biomarkers in physiological and pathophysiological processes involving cancer initiation and progression. MiR-492 is encoded by a pseudogene, has a key role in some human cancer cells and its overexpression in tissues, and it has been proposed that it can be used as a good biomarker for management and early diagnosis of some cancers including breast cancer, colorectal and ovarian cancer, hepatocellular cancer, retinoblastoma and pancreatic cancer. The aim of this review was to summarize the data of MiR-492 for early diagnosis and treatment of some types of related cancers.",

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AU - Taghizadeh, Eskandar

AU - Taheri, Forough

AU - Rostami, Daryoush

AU - Renani, Pedram G.

AU - Ferns, Gordon A.

AU - Pasdar, Alireza

AU - Mobarhan, Majid G.

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AB - Recent studies have led to a more detailed understanding of the roles played by microRNAs in health and disease, and their potential use as biomarkers in physiological and pathophysiological processes involving cancer initiation and progression. MiR-492 is encoded by a pseudogene, has a key role in some human cancer cells and its overexpression in tissues, and it has been proposed that it can be used as a good biomarker for management and early diagnosis of some cancers including breast cancer, colorectal and ovarian cancer, hepatocellular cancer, retinoblastoma and pancreatic cancer. The aim of this review was to summarize the data of MiR-492 for early diagnosis and treatment of some types of related cancers.

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KW - Colorectal cancer

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MiR-492 as an important biomarker for early diagnosis and targeted treatment in different cancers

Abstract

Keywords

UN SDGs

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