Mixed leptospira infections in a diverse reservoir host community, Madagascar, 2013–2015

Mark Moseley*, Soanandrasana Rahelinirina, Minoarisoa Rajerison, Benoit Garin, Stuart Piertney, Sandra Telfer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

We identified mixed infections of pathogenic Leptospira in small mammals across a landscape-scale study area in Madagascar by using primers targeting different Leptospira spp. Using targeted primers increased prevalence estimates and evidence for transmission between endemic and invasive hosts. Future studies should assess rodentborne transmission of Leptospira to humans.

Original languageEnglish
Pages (from-to)1138-1140
Number of pages3
JournalEmerging Infectious Diseases
Volume24
Issue number6
Early online date7 May 2018
DOIs
Publication statusPublished - 30 Jun 2018

Bibliographical note

We thank the staff of the Plague Central Laboratory, Institut Pasteur de Madagascar, for field and technical assistance, especially Fehivola Andriamiarimanana for DNA extractions and 16S qPCR assays; Toky Randriamoria for help with field work and identifying endemic species; and Mathieu Picardeau for supplying isolates used as positive controls in PCR experiments.

This work was supported by a Wellcome Trust Senior Fellowship (no. 095171 to S.T.), the Biotechnology and Biological Sciences Research Council (grant no. BB/M010996/1), and the University of Aberdeen Environment and Food Security theme.

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