Monoclonal gammopathy of undetermined significance as viewed by haematology healthcare professionals

Charlene M. McShane, Blain Murphy, Kah Heng Lim, Lesley A. Anderson* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Objectives: To investigate the words and descriptions used by haematology healthcare professionals (HCPs) to describe monoclonal gammopathy of undetermined significance (MGUS) to their patients. Methods: A cross-sectional survey of haematology HCPs attending an annual haematology conference was undertaken. Content analysis was applied to the returned qualitative responses. Results: In total, 55 people, many of whom were doctors (n = 32; 58.2%), responded. The majority of respondents reported using simple terminology such as “abnormal protein” to describe MGUS to their patients. Some reported using analogies that the patient was more likely to be familiar with, such as comparing a paraprotein to the finding of a mole or lump. Education level, age and cognitive ability were cited as important factors in deciding how and whether information was relayed to patients. Many respondents supported frequent follow-up and the transfer of low-risk MGUS patients to primary care. However, several highlighted a lack of awareness and understanding of MGUS outside of haematology, particularly within primary care. Only 41.8% of respondents reported providing all of their patients with an information leaflet. Conclusions: With an ageing population, it is important to consider management strategies for MGUS patients. Our findings will assist those in making these arrangements.

Original languageEnglish
Pages (from-to)20-26
Number of pages7
JournalEuropean Journal of Haematology
Issue number1
Early online date14 Nov 2017
Publication statusPublished - Jan 2018

Bibliographical note

Cancer Research UK Population Science Postdoctoral Research Fellowship. Grant Number: C51094/A18267


  • communication aids
  • haematology
  • healthcare professionals
  • management (follow-up)
  • monoclonal gammopathy of undetermined significance
  • myeloma


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