Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019

Mohammad Mahdi Rashidi; Sahar Saeedi Moghaddam; Sina Azadnajafabad; Esmaeil Mohammadi; Amirmohammad Khalaji; Mohammad Reza Malekpour; Mohammad Keykhaei; Negar Rezaei; Zahra Esfahani; Nazila Rezaei; Ali H. Mokdad; Christopher J.L. Murray; Mohsen Naghavi; Bagher Larijani; Farshad Farzadfar; Mohsen Abbasi-Kangevari; Zeinab Abbasi-Kangevari; Samar Abd ElHafeez; Sherief Abd-Elsalam; Meriem Abdoun; Eman Abu-Gharbieh; Aqeel Ahmad; Ayman Ahmed; Sayer Al-Azzam; Rajaa M. Al-Raddadi; Ala'a B. AlTammemi; Javad Aminian Dehkordi; Mehrdad Amir Behghadami; Jalal Arabloo; Mohammad Athar; Seyyed Shamsadin Athari; Mahsa Babaei; Hassan Babamohamadi; Nayereh Baghcheghi; Sara Bagherieh; Hamid Reza Baradaran; Akshaya Srikanth Bhagavathula; Vijayalakshmi S. Bhojaraja; Milad Bonakdar Hashemi; Luciana Aparecida Campos; Azizallah Dehghan; Muhammed Elhadi; Waseem El-Huneidi; Ali Fatehizadeh; Alireza Feizkhah; Fataneh Ghadirian; Ali Gholami; Samer Hamidi; Hadi Hassankhani; Mahsa Heidari-Foroozan; GBD 2019 NAME Kidney Dysfunction Risk Factor Collaborators

doi:10.1093/ckj/sfad279

Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019

Mohammad Mahdi Rashidi, Sahar Saeedi Moghaddam, Sina Azadnajafabad, Esmaeil Mohammadi, Amirmohammad Khalaji, Mohammad Reza Malekpour, Mohammad Keykhaei, Negar Rezaei, Zahra Esfahani, Nazila Rezaei, Ali H. Mokdad, Christopher J.L. Murray, Mohsen Naghavi, Bagher Larijani, Farshad Farzadfar^*, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Samar Abd ElHafeez, Sherief Abd-Elsalam, Meriem AbdounEman Abu-Gharbieh, Aqeel Ahmad, Ayman Ahmed, Sayer Al-Azzam, Rajaa M. Al-Raddadi, Ala'a B. AlTammemi, Javad Aminian Dehkordi, Mehrdad Amir Behghadami, Jalal Arabloo, Mohammad Athar, Seyyed Shamsadin Athari, Mahsa Babaei, Hassan Babamohamadi, Nayereh Baghcheghi, Sara Bagherieh, Hamid Reza Baradaran, Akshaya Srikanth Bhagavathula, Vijayalakshmi S. Bhojaraja, Milad Bonakdar Hashemi, Luciana Aparecida Campos, Azizallah Dehghan, Muhammed Elhadi, Waseem El-Huneidi, Ali Fatehizadeh, Alireza Feizkhah, Fataneh Ghadirian, Ali Gholami, Samer Hamidi, Hadi Hassankhani, Mahsa Heidari-Foroozan, GBD 2019 NAME Kidney Dysfunction Risk Factor Collaborators

^*Corresponding author for this work

Applied Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Background. The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. Methods. The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disability-adjusted life years (DALYs), and other epidemiological indicators of burden. To provide a better insight into the differences in the level of social, cultural, and economic factors, the Socio-Demographic Index (SDI) was used. Results. In the NAME region in 2019, the number of deaths attributed to kidney dysfunction was 296 632 (95% uncertainty interval: 249 965-343 962), which was about 2.5 times higher than in the year 1990. Afghanistan, Egypt, and Saudi Arabia had the highest, and Kuwait, Turkey, and Iran (Islamic Republic of) had the lowest age-standardized rate of DALYs attributed to kidney dysfunction in the region in 2019. Kidney dysfunction was accounted as a risk factor for ischemic heart disease, chronic kidney disease, stroke, and peripheral artery disease with 150 471, 111 812, 34 068, and 281 attributable deaths, respectively, in 2019 in the region. In 2019, both low-SDI and high-SDI countries in the region experienced higher burdens associated with kidney dysfunction compared to other countries. Conclusions. Kidney dysfunction increases the risk of cardiovascular diseases burden and accounted for more deaths attributable to cardiovascular diseases than chronic kidney disease in the region in 2019. Hence, policymakers in the NAME region should prioritize kidney disease prevention and control, recognizing that neglecting its impact on other diseases is a key limitation in its management.

Original language	English
Article number	sfad279
Pages (from-to)	1-13
Number of pages	13
Journal	Clinical Kidney Journal
Volume	17
Issue number	1
Early online date	17 Nov 2023
DOIs	https://doi.org/10.1093/ckj/sfad279
Publication status	Published - 29 Jan 2024

Bibliographical note

The authors would like to thank the hard work of the staff of the Institute for Health Metrics and Evaluation (IHME) for providing the best possible epidemiologic estimation of diseases in almost all regions and countries of the world, trying to reduce and eliminate poverty of knowledge and information about the diseases globally. Also, the core team authors sincerely thank all the collaborators of the GBD 2019 study who contributed to this study by providing data or a precise review of the manuscript.

Publisher Copyright:
© The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords

cardiovascular diseases
chronic kidney disease
global burden of disease
kidney dysfunction
mortality

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/ckj/sfad279Licence: CC BY

Rashidi_etal_CKJ_Mortality_And_Disability_VoR
© The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Final published version, 2.02 MBLicence: CC BY

Cite this

Rashidi, M. M., Moghaddam, S. S., Azadnajafabad, S., Mohammadi, E., Khalaji, A., Malekpour, M. R., Keykhaei, M., Rezaei, N., Esfahani, Z., Rezaei, N., Mokdad, A. H., Murray, C. J. L., Naghavi, M., Larijani, B., Farzadfar, F., Abbasi-Kangevari, M., Abbasi-Kangevari, Z., ElHafeez, S. A., Abd-Elsalam, S., ... GBD 2019 NAME Kidney Dysfunction Risk Factor Collaborators (2024). Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019. Clinical Kidney Journal, 17(1), 1-13. Article sfad279. https://doi.org/10.1093/ckj/sfad279

Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019. / Rashidi, Mohammad Mahdi; Moghaddam, Sahar Saeedi; Azadnajafabad, Sina et al.
In: Clinical Kidney Journal, Vol. 17, No. 1, sfad279, 29.01.2024, p. 1-13.

Research output: Contribution to journal › Article › peer-review

Rashidi, MM, Moghaddam, SS, Azadnajafabad, S, Mohammadi, E, Khalaji, A, Malekpour, MR, Keykhaei, M, Rezaei, N, Esfahani, Z, Rezaei, N, Mokdad, AH, Murray, CJL, Naghavi, M, Larijani, B, Farzadfar, F, Abbasi-Kangevari, M, Abbasi-Kangevari, Z, ElHafeez, SA, Abd-Elsalam, S, Abdoun, M, Abu-Gharbieh, E, Ahmad, A, Ahmed, A, Al-Azzam, S, Al-Raddadi, RM, AlTammemi, AB, Dehkordi, JA, Behghadami, MA, Arabloo, J, Athar, M, Athari, SS, Babaei, M, Babamohamadi, H, Baghcheghi, N, Bagherieh, S, Baradaran, HR, Bhagavathula, AS, Bhojaraja, VS, Hashemi, MB, Campos, LA, Dehghan, A, Elhadi, M, El-Huneidi, W, Fatehizadeh, A, Feizkhah, A, Ghadirian, F, Gholami, A, Hamidi, S, Hassankhani, H, Heidari-Foroozan, M & GBD 2019 NAME Kidney Dysfunction Risk Factor Collaborators 2024, 'Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019', Clinical Kidney Journal, vol. 17, no. 1, sfad279, pp. 1-13. https://doi.org/10.1093/ckj/sfad279

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title = "Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019",

abstract = "Background. The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. Methods. The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disability-adjusted life years (DALYs), and other epidemiological indicators of burden. To provide a better insight into the differences in the level of social, cultural, and economic factors, the Socio-Demographic Index (SDI) was used. Results. In the NAME region in 2019, the number of deaths attributed to kidney dysfunction was 296 632 (95% uncertainty interval: 249 965-343 962), which was about 2.5 times higher than in the year 1990. Afghanistan, Egypt, and Saudi Arabia had the highest, and Kuwait, Turkey, and Iran (Islamic Republic of) had the lowest age-standardized rate of DALYs attributed to kidney dysfunction in the region in 2019. Kidney dysfunction was accounted as a risk factor for ischemic heart disease, chronic kidney disease, stroke, and peripheral artery disease with 150 471, 111 812, 34 068, and 281 attributable deaths, respectively, in 2019 in the region. In 2019, both low-SDI and high-SDI countries in the region experienced higher burdens associated with kidney dysfunction compared to other countries. Conclusions. Kidney dysfunction increases the risk of cardiovascular diseases burden and accounted for more deaths attributable to cardiovascular diseases than chronic kidney disease in the region in 2019. Hence, policymakers in the NAME region should prioritize kidney disease prevention and control, recognizing that neglecting its impact on other diseases is a key limitation in its management.",

keywords = "cardiovascular diseases, chronic kidney disease, global burden of disease, kidney dysfunction, mortality",

author = "Rashidi, {Mohammad Mahdi} and Moghaddam, {Sahar Saeedi} and Sina Azadnajafabad and Esmaeil Mohammadi and Amirmohammad Khalaji and Malekpour, {Mohammad Reza} and Mohammad Keykhaei and Negar Rezaei and Zahra Esfahani and Nazila Rezaei and Mokdad, {Ali H.} and Murray, {Christopher J.L.} and Mohsen Naghavi and Bagher Larijani and Farshad Farzadfar and Mohsen Abbasi-Kangevari and Zeinab Abbasi-Kangevari and ElHafeez, {Samar Abd} and Sherief Abd-Elsalam and Meriem Abdoun and Eman Abu-Gharbieh and Aqeel Ahmad and Ayman Ahmed and Sayer Al-Azzam and Al-Raddadi, {Rajaa M.} and AlTammemi, {Ala'a B.} and Dehkordi, {Javad Aminian} and Behghadami, {Mehrdad Amir} and Jalal Arabloo and Mohammad Athar and Athari, {Seyyed Shamsadin} and Mahsa Babaei and Hassan Babamohamadi and Nayereh Baghcheghi and Sara Bagherieh and Baradaran, {Hamid Reza} and Bhagavathula, {Akshaya Srikanth} and Bhojaraja, {Vijayalakshmi S.} and Hashemi, {Milad Bonakdar} and Campos, {Luciana Aparecida} and Azizallah Dehghan and Muhammed Elhadi and Waseem El-Huneidi and Ali Fatehizadeh and Alireza Feizkhah and Fataneh Ghadirian and Ali Gholami and Samer Hamidi and Hadi Hassankhani and Mahsa Heidari-Foroozan and {GBD 2019 NAME Kidney Dysfunction Risk Factor Collaborators}",

note = "The authors would like to thank the hard work of the staff of the Institute for Health Metrics and Evaluation (IHME) for providing the best possible epidemiologic estimation of diseases in almost all regions and countries of the world, trying to reduce and eliminate poverty of knowledge and information about the diseases globally. Also, the core team authors sincerely thank all the collaborators of the GBD 2019 study who contributed to this study by providing data or a precise review of the manuscript. Publisher Copyright: {\textcopyright} The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.",

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month = jan,

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doi = "10.1093/ckj/sfad279",

language = "English",

volume = "17",

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journal = "Clinical Kidney Journal",

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T1 - Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction

T2 - a systematic analysis for the Global Burden of Disease Study 2019

AU - Rashidi, Mohammad Mahdi

AU - Moghaddam, Sahar Saeedi

AU - Azadnajafabad, Sina

AU - Mohammadi, Esmaeil

AU - Khalaji, Amirmohammad

AU - Malekpour, Mohammad Reza

AU - Keykhaei, Mohammad

AU - Rezaei, Negar

AU - Esfahani, Zahra

AU - Rezaei, Nazila

AU - Mokdad, Ali H.

AU - Murray, Christopher J.L.

AU - Naghavi, Mohsen

AU - Larijani, Bagher

AU - Farzadfar, Farshad

AU - Abbasi-Kangevari, Mohsen

AU - Abbasi-Kangevari, Zeinab

AU - ElHafeez, Samar Abd

AU - Abd-Elsalam, Sherief

AU - Abdoun, Meriem

AU - Abu-Gharbieh, Eman

AU - Ahmad, Aqeel

AU - Ahmed, Ayman

AU - Al-Azzam, Sayer

AU - Al-Raddadi, Rajaa M.

AU - AlTammemi, Ala'a B.

AU - Dehkordi, Javad Aminian

AU - Behghadami, Mehrdad Amir

AU - Arabloo, Jalal

AU - Athar, Mohammad

AU - Athari, Seyyed Shamsadin

AU - Babaei, Mahsa

AU - Babamohamadi, Hassan

AU - Baghcheghi, Nayereh

AU - Bagherieh, Sara

AU - Baradaran, Hamid Reza

AU - Bhagavathula, Akshaya Srikanth

AU - Bhojaraja, Vijayalakshmi S.

AU - Hashemi, Milad Bonakdar

AU - Campos, Luciana Aparecida

AU - Dehghan, Azizallah

AU - Elhadi, Muhammed

AU - El-Huneidi, Waseem

AU - Fatehizadeh, Ali

AU - Feizkhah, Alireza

AU - Ghadirian, Fataneh

AU - Gholami, Ali

AU - Hamidi, Samer

AU - Hassankhani, Hadi

AU - Heidari-Foroozan, Mahsa

AU - GBD 2019 NAME Kidney Dysfunction Risk Factor Collaborators

N1 - The authors would like to thank the hard work of the staff of the Institute for Health Metrics and Evaluation (IHME) for providing the best possible epidemiologic estimation of diseases in almost all regions and countries of the world, trying to reduce and eliminate poverty of knowledge and information about the diseases globally. Also, the core team authors sincerely thank all the collaborators of the GBD 2019 study who contributed to this study by providing data or a precise review of the manuscript. Publisher Copyright: © The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PY - 2024/1/29

Y1 - 2024/1/29

N2 - Background. The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. Methods. The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disability-adjusted life years (DALYs), and other epidemiological indicators of burden. To provide a better insight into the differences in the level of social, cultural, and economic factors, the Socio-Demographic Index (SDI) was used. Results. In the NAME region in 2019, the number of deaths attributed to kidney dysfunction was 296 632 (95% uncertainty interval: 249 965-343 962), which was about 2.5 times higher than in the year 1990. Afghanistan, Egypt, and Saudi Arabia had the highest, and Kuwait, Turkey, and Iran (Islamic Republic of) had the lowest age-standardized rate of DALYs attributed to kidney dysfunction in the region in 2019. Kidney dysfunction was accounted as a risk factor for ischemic heart disease, chronic kidney disease, stroke, and peripheral artery disease with 150 471, 111 812, 34 068, and 281 attributable deaths, respectively, in 2019 in the region. In 2019, both low-SDI and high-SDI countries in the region experienced higher burdens associated with kidney dysfunction compared to other countries. Conclusions. Kidney dysfunction increases the risk of cardiovascular diseases burden and accounted for more deaths attributable to cardiovascular diseases than chronic kidney disease in the region in 2019. Hence, policymakers in the NAME region should prioritize kidney disease prevention and control, recognizing that neglecting its impact on other diseases is a key limitation in its management.

AB - Background. The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. Methods. The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disability-adjusted life years (DALYs), and other epidemiological indicators of burden. To provide a better insight into the differences in the level of social, cultural, and economic factors, the Socio-Demographic Index (SDI) was used. Results. In the NAME region in 2019, the number of deaths attributed to kidney dysfunction was 296 632 (95% uncertainty interval: 249 965-343 962), which was about 2.5 times higher than in the year 1990. Afghanistan, Egypt, and Saudi Arabia had the highest, and Kuwait, Turkey, and Iran (Islamic Republic of) had the lowest age-standardized rate of DALYs attributed to kidney dysfunction in the region in 2019. Kidney dysfunction was accounted as a risk factor for ischemic heart disease, chronic kidney disease, stroke, and peripheral artery disease with 150 471, 111 812, 34 068, and 281 attributable deaths, respectively, in 2019 in the region. In 2019, both low-SDI and high-SDI countries in the region experienced higher burdens associated with kidney dysfunction compared to other countries. Conclusions. Kidney dysfunction increases the risk of cardiovascular diseases burden and accounted for more deaths attributable to cardiovascular diseases than chronic kidney disease in the region in 2019. Hence, policymakers in the NAME region should prioritize kidney disease prevention and control, recognizing that neglecting its impact on other diseases is a key limitation in its management.

KW - cardiovascular diseases

KW - chronic kidney disease

KW - global burden of disease

KW - kidney dysfunction

KW - mortality

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DO - 10.1093/ckj/sfad279

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Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019

Abstract

Bibliographical note

Keywords

UN SDGs

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