Neuronal Growth Cone Guidance by Physiological DC Electric Fields

Ann M. Rajnicek*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


Neurons exist within a complex milieu, in which they are exposed to many factors that affect their growth, survival, and function. These factors can be grouped into three general categories: chemical (growth factors, neurotransmitters, or adhesion molecules, which can be either soluble or substratum bound), physical (contours of the three-dimensional space surrounding the cell), and electrical (standing extracellular voltage gradients). During development and repair, neurons use these environmental factors to guide the tips of growing axons, called growth cones, to appropriate targets (e.g., another neuron or a.

Original languageEnglish
Title of host publicationThe Physiology of Bioelectricity in Development, Tissue Regeneration and Cancer
PublisherCRC Press
Number of pages32
ISBN (Electronic)9781439837245, 9780429105555
ISBN (Print)9781138077836
Publication statusPublished - 1 Jan 2016

Bibliographical note

Publisher Copyright:
© 2011 by Taylor and Francis Group, LLC.


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