Novel Non-Target Analysis for Fluorine Compounds Using ICPMS/MS and HPLC-ICPMS/MS

Nor Laili A. Jamari, J. Frederik Dohmann, Andrea Raab, Eva M. Krupp, Jorg Feldmann* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)
20 Downloads (Pure)


Measuring sub ppm levels of fluorine (F) directly with an commercial ICPMS is not possible due to high ionisation potential of F. Mixing of barium and fluorine solution enabled a new approach in fluorine analysis through the formation of the polyatomic ion BaF+ using ICPMS/MS. Different parameters such as reaction gas flow rate, sampling position, carrier and make up gas flow rate, waiting and acquisition time as well as RF power were optimized in order to obtain the highest possible sensitivities for 138Ba19F+, as those parameters were important for polyatomic ion formation, avoiding barium oxide and barium hydroxide ions interference and sensitive detection in MS/MS. A limit of detection (LOD) of 0.043 mg L-1 was achieved with a good recovery of fluoride spiked in deionised water. For fluorine speciation analysis, coupling of anion exchange chromatography online to ICPMS/MS allowed separation and fluorine specific detection of fluoride and fluoroacetate. The response was compound independent as expected for ICPMS. The LOD for fluoride and fluoroacetate were 0.022 mg L-1 and 0.11 mg L-1 respectively. Both compounds were baseline separated and detected quantitatively, making this newly developed method a promising candidate for non-target fluorine speciation analysis in environmental samples.
Original languageEnglish
Pages (from-to)942-950
Number of pages9
JournalJournal of Analytical Atomic Spectrometry
Issue number5
Early online date6 Apr 2017
Publication statusPublished - 1 May 2017

Bibliographical note

NLAJ thanks the Malaysian Government (Grant number: RG12824-10) and National Defence University of Malaysia for financial support throughout the study period, while JFD thanks the Erasmus programme of the EU. Special thanks to Noriyuki Yamada from Agilent Technologies for the guidance using the ICPMS/MS. The authors thank Dr Corny Brombach for the artwork.


Dive into the research topics of 'Novel Non-Target Analysis for Fluorine Compounds Using ICPMS/MS and HPLC-ICPMS/MS'. Together they form a unique fingerprint.

Cite this