Abstract
Parvalbumin-positive GABAergic interneurons in cortical circuits are hypothesized to control cognitive function. To test this idea directly, we functionally removed parvalbumin-positive interneurons selectively from hippocampal CA1 in mice. We found that parvalbumin-positive interneurons are dispensable for spatial reference, but are essential for spatial working memory.
Original language | English |
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Pages (from-to) | 297-299 |
Number of pages | 3 |
Journal | Nature Neuroscience |
Volume | 14 |
Issue number | 3 |
Early online date | 30 Jan 2011 |
DOIs | |
Publication status | Published - Mar 2011 |