Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Nasim Mavaddat; Daniel Barrowdale; Irene L Andrulis; Susan M Domchek; Diana Eccles; Heli Nevanlinna; Susan J Ramus; Amanda Spurdle; Mark Robson; Mark Sherman; Anna Marie Mulligan; Fergus J Couch; Christoph Engel; Lesley McGuffog; Sue Healey; Olga M Sinilnikova; Melissa C Southey; Mary Beth Terry; David Goldgar; Frances O'Malley; Esther M John; Ramunas Janavicius; Laima Tihomirova; Thomas V O Hansen; Finn C Nielsen; Ana Osorio; Alexandra Stavropoulou; Javier Benítez; Siranoush Manoukian; Bernard Peissel; Monica Barile; Sara Volorio; Barbara Pasini; Riccardo Dolcetti; Anna Laura Putignano; Laura Ottini; Paolo Radice; Ute Hamann; Muhammad U Rashid; Frans B Hogervorst; Mieke Kriege; Rob B van der Luijt; Susan Peock; Debra Frost; D Gareth Evans; Carole Brewer; Lisa Walker; Mark T Rogers; Lucy E Side; HEBON; Zosia Miedzybrodzka

doi:10.1158/1055-9965.EPI-11-0775

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Nasim Mavaddat, Daniel Barrowdale, Irene L Andrulis, Susan M Domchek, Diana Eccles, Heli Nevanlinna, Susan J Ramus, Amanda Spurdle, Mark Robson, Mark Sherman, Anna Marie Mulligan, Fergus J Couch, Christoph Engel, Lesley McGuffog, Sue Healey, Olga M Sinilnikova, Melissa C Southey, Mary Beth Terry, David Goldgar, Frances O'MalleyEsther M John, Ramunas Janavicius, Laima Tihomirova, Thomas V O Hansen, Finn C Nielsen, Ana Osorio, Alexandra Stavropoulou, Javier Benítez, Siranoush Manoukian, Bernard Peissel, Monica Barile, Sara Volorio, Barbara Pasini, Riccardo Dolcetti, Anna Laura Putignano, Laura Ottini, Paolo Radice, Ute Hamann, Muhammad U Rashid, Frans B Hogervorst, Mieke Kriege, Rob B van der Luijt, Susan Peock, Debra Frost, D Gareth Evans, Carole Brewer, Lisa Walker, Mark T Rogers, Lucy E Side, HEBON, Zosia Miedzybrodzka

Research output: Contribution to journal › Article › peer-review

500 Citations (Scopus)

Abstract

Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.

Original language	English
Pages (from-to)	134-147
Number of pages	14
Journal	Cancer Epidemiology, Biomarkers and Prevention
Volume	21
Issue number	1
Early online date	5 Dec 2011
DOIs	https://doi.org/10.1158/1055-9965.EPI-11-0775
Publication status	Published - 21 Jan 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1158/1055-9965.EPI-11-0775

Cite this

Mavaddat, N., Barrowdale, D., Andrulis, I. L., Domchek, S. M., Eccles, D., Nevanlinna, H., Ramus, S. J., Spurdle, A., Robson, M., Sherman, M., Mulligan, A. M., Couch, F. J., Engel, C., McGuffog, L., Healey, S., Sinilnikova, O. M., Southey, M. C., Terry, M. B., Goldgar, D., ... Miedzybrodzka, Z. (2012). Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). Cancer Epidemiology, Biomarkers and Prevention, 21(1), 134-147. https://doi.org/10.1158/1055-9965.EPI-11-0775

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). / Mavaddat, Nasim; Barrowdale, Daniel; Andrulis, Irene L et al.
In: Cancer Epidemiology, Biomarkers and Prevention, Vol. 21, No. 1, 21.01.2012, p. 134-147.

Research output: Contribution to journal › Article › peer-review

Mavaddat, N, Barrowdale, D, Andrulis, IL, Domchek, SM, Eccles, D, Nevanlinna, H, Ramus, SJ, Spurdle, A, Robson, M, Sherman, M, Mulligan, AM, Couch, FJ, Engel, C, McGuffog, L, Healey, S, Sinilnikova, OM, Southey, MC, Terry, MB, Goldgar, D, O'Malley, F, John, EM, Janavicius, R, Tihomirova, L, Hansen, TVO, Nielsen, FC, Osorio, A, Stavropoulou, A, Benítez, J, Manoukian, S, Peissel, B, Barile, M, Volorio, S, Pasini, B, Dolcetti, R, Putignano, AL, Ottini, L, Radice, P, Hamann, U, Rashid, MU, Hogervorst, FB, Kriege, M, van der Luijt, RB, Peock, S, Frost, D, Evans, DG, Brewer, C, Walker, L, Rogers, MT, Side, LE, HEBON & Miedzybrodzka, Z 2012, 'Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)', Cancer Epidemiology, Biomarkers and Prevention, vol. 21, no. 1, pp. 134-147. https://doi.org/10.1158/1055-9965.EPI-11-0775

@article{977a1a06d4af418e88191d27e4e3bfd4,

title = "Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)",

abstract = "Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.",

author = "Nasim Mavaddat and Daniel Barrowdale and Andrulis, {Irene L} and Domchek, {Susan M} and Diana Eccles and Heli Nevanlinna and Ramus, {Susan J} and Amanda Spurdle and Mark Robson and Mark Sherman and Mulligan, {Anna Marie} and Couch, {Fergus J} and Christoph Engel and Lesley McGuffog and Sue Healey and Sinilnikova, {Olga M} and Southey, {Melissa C} and Terry, {Mary Beth} and David Goldgar and Frances O'Malley and John, {Esther M} and Ramunas Janavicius and Laima Tihomirova and Hansen, {Thomas V O} and Nielsen, {Finn C} and Ana Osorio and Alexandra Stavropoulou and Javier Ben{\'i}tez and Siranoush Manoukian and Bernard Peissel and Monica Barile and Sara Volorio and Barbara Pasini and Riccardo Dolcetti and Putignano, {Anna Laura} and Laura Ottini and Paolo Radice and Ute Hamann and Rashid, {Muhammad U} and Hogervorst, {Frans B} and Mieke Kriege and {van der Luijt}, {Rob B} and Susan Peock and Debra Frost and Evans, {D Gareth} and Carole Brewer and Lisa Walker and Rogers, {Mark T} and Side, {Lucy E} and HEBON and Zosia Miedzybrodzka",

year = "2012",

month = jan,

day = "21",

doi = "10.1158/1055-9965.EPI-11-0775",

language = "English",

volume = "21",

pages = "134--147",

journal = "Cancer Epidemiology, Biomarkers and Prevention",

issn = "1538-7755",

publisher = "AMER ASSOC CANCER RESEARCH",

number = "1",

}

TY - JOUR

T1 - Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers

T2 - results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

AU - Mavaddat, Nasim

AU - Barrowdale, Daniel

AU - Andrulis, Irene L

AU - Domchek, Susan M

AU - Eccles, Diana

AU - Nevanlinna, Heli

AU - Ramus, Susan J

AU - Spurdle, Amanda

AU - Robson, Mark

AU - Sherman, Mark

AU - Mulligan, Anna Marie

AU - Couch, Fergus J

AU - Engel, Christoph

AU - McGuffog, Lesley

AU - Healey, Sue

AU - Sinilnikova, Olga M

AU - Southey, Melissa C

AU - Terry, Mary Beth

AU - Goldgar, David

AU - O'Malley, Frances

AU - John, Esther M

AU - Janavicius, Ramunas

AU - Tihomirova, Laima

AU - Hansen, Thomas V O

AU - Nielsen, Finn C

AU - Osorio, Ana

AU - Stavropoulou, Alexandra

AU - Benítez, Javier

AU - Manoukian, Siranoush

AU - Peissel, Bernard

AU - Barile, Monica

AU - Volorio, Sara

AU - Pasini, Barbara

AU - Dolcetti, Riccardo

AU - Putignano, Anna Laura

AU - Ottini, Laura

AU - Radice, Paolo

AU - Hamann, Ute

AU - Rashid, Muhammad U

AU - Hogervorst, Frans B

AU - Kriege, Mieke

AU - van der Luijt, Rob B

AU - Peock, Susan

AU - Frost, Debra

AU - Evans, D Gareth

AU - Brewer, Carole

AU - Walker, Lisa

AU - Rogers, Mark T

AU - Side, Lucy E

AU - HEBON

AU - Miedzybrodzka, Zosia

PY - 2012/1/21

Y1 - 2012/1/21

N2 - Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.

AB - Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.

U2 - 10.1158/1055-9965.EPI-11-0775

DO - 10.1158/1055-9965.EPI-11-0775

M3 - Article

C2 - 22144499

SN - 1538-7755

VL - 21

SP - 134

EP - 147

JO - Cancer Epidemiology, Biomarkers and Prevention

JF - Cancer Epidemiology, Biomarkers and Prevention

IS - 1

ER -

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this