Perioperative use of dexamethasone: an international study from the PAIN OUT registry

Drew McMichael; Philipp Baumbach; Marcus Komann; Ruth Edry; Valeria Martinez; Martha Melo; Esther Pogatzki-Zahn; Teresa Santeularia; Ulrike Stamer; Turgay Tuna; Hongwei Wang; Winfried Meissner; Ruth Zaslansky; Patrice Forget

doi:10.1016/j.bja.2024.01.018

Perioperative use of dexamethasone: an international study from the PAIN OUT registry

Drew McMichael, Philipp Baumbach, Marcus Komann, Ruth Edry, Valeria Martinez, Martha Melo, Esther Pogatzki-Zahn, Teresa Santeularia, Ulrike Stamer, Turgay Tuna, Hongwei Wang, Winfried Meissner, Ruth Zaslansky, Patrice Forget^* (Corresponding Author)

^*Corresponding author for this work

Research output: Contribution to journal › Letter › peer-review

Abstract

Perioperative dexamethasone has been used as an effective agent to prevent postoperative nausea and vomiting (PONV).1 Glucocorticosteroids can reduce time to onset and increase duration of regional anaesthesia, and might improve postoperative analgesia.2,3 Because of its effectiveness in preventing PONV, its place in guidelines and lack of knowledge regarding its real-world use, it is important to document factors associated with dexamethasone use. We aimed to describe dexamethasone use in the international registry and quality improvement project PAIN OUT and to identify associated factors.

Original language	English
Pages (from-to)	824-826
Number of pages	3
Journal	British Journal of Anaesthesia
Volume	132
Issue number	4
Early online date	15 Feb 2024
DOIs	https://doi.org/10.1016/j.bja.2024.01.018
Publication status	Published - Apr 2024

Bibliographical note

The authors would like to recognise the support given by the entire PAIN OUT consortium and collaborating centres.

Data Availability Statement

The dataset analysed during the current study is available from the corresponding author on reasonable request and after approval of the PAIN OUT steering committee.

Keywords

analgesia
antiemetic
dexamethasone
nausea
vomiting

Access to Document

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Cite this

McMichael, D., Baumbach, P., Komann, M., Edry, R., Martinez, V., Melo, M., Pogatzki-Zahn, E., Santeularia, T., Stamer, U., Tuna, T., Wang, H., Meissner, W., Zaslansky, R., & Forget, P. (2024). Perioperative use of dexamethasone: an international study from the PAIN OUT registry. British Journal of Anaesthesia, 132(4), 824-826. https://doi.org/10.1016/j.bja.2024.01.018

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abstract = "Perioperative dexamethasone has been used as an effective agent to prevent postoperative nausea and vomiting (PONV).1 Glucocorticosteroids can reduce time to onset and increase duration of regional anaesthesia, and might improve postoperative analgesia.2,3 Because of its effectiveness in preventing PONV, its place in guidelines and lack of knowledge regarding its real-world use, it is important to document factors associated with dexamethasone use. We aimed to describe dexamethasone use in the international registry and quality improvement project PAIN OUT and to identify associated factors.",

keywords = "analgesia, antiemetic, dexamethasone, nausea, vomiting",

author = "Drew McMichael and Philipp Baumbach and Marcus Komann and Ruth Edry and Valeria Martinez and Martha Melo and Esther Pogatzki-Zahn and Teresa Santeularia and Ulrike Stamer and Turgay Tuna and Hongwei Wang and Winfried Meissner and Ruth Zaslansky and Patrice Forget",

note = "The authors would like to recognise the support given by the entire PAIN OUT consortium and collaborating centres.",

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doi = "10.1016/j.bja.2024.01.018",

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T2 - an international study from the PAIN OUT registry

AU - McMichael, Drew

AU - Baumbach, Philipp

AU - Komann, Marcus

AU - Edry, Ruth

AU - Martinez, Valeria

AU - Melo, Martha

AU - Pogatzki-Zahn, Esther

AU - Santeularia, Teresa

AU - Stamer, Ulrike

AU - Tuna, Turgay

AU - Wang, Hongwei

AU - Meissner, Winfried

AU - Zaslansky, Ruth

AU - Forget, Patrice

N1 - The authors would like to recognise the support given by the entire PAIN OUT consortium and collaborating centres.

PY - 2024/4

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N2 - Perioperative dexamethasone has been used as an effective agent to prevent postoperative nausea and vomiting (PONV).1 Glucocorticosteroids can reduce time to onset and increase duration of regional anaesthesia, and might improve postoperative analgesia.2,3 Because of its effectiveness in preventing PONV, its place in guidelines and lack of knowledge regarding its real-world use, it is important to document factors associated with dexamethasone use. We aimed to describe dexamethasone use in the international registry and quality improvement project PAIN OUT and to identify associated factors.

AB - Perioperative dexamethasone has been used as an effective agent to prevent postoperative nausea and vomiting (PONV).1 Glucocorticosteroids can reduce time to onset and increase duration of regional anaesthesia, and might improve postoperative analgesia.2,3 Because of its effectiveness in preventing PONV, its place in guidelines and lack of knowledge regarding its real-world use, it is important to document factors associated with dexamethasone use. We aimed to describe dexamethasone use in the international registry and quality improvement project PAIN OUT and to identify associated factors.

KW - analgesia

KW - antiemetic

KW - dexamethasone

KW - nausea

KW - vomiting

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U2 - 10.1016/j.bja.2024.01.018

DO - 10.1016/j.bja.2024.01.018

M3 - Letter

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SN - 0007-0912

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SP - 824

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JO - British Journal of Anaesthesia

JF - British Journal of Anaesthesia

IS - 4

ER -

Perioperative use of dexamethasone: an international study from the PAIN OUT registry

Abstract

Bibliographical note

Data Availability Statement

Keywords

Access to Document

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Cite this