Polysomnography in humans and animal models: basic procedures and analysis

Pablo Torterolo, Joaquín Gonzalez, Santiago Castro-Zaballa, Matías Cavelli, Alejandra Mondino, Claudia Pascovich, Nicolás Rubido, Eric Murillo-Rodríguez, Giancarlo Vanini

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)


Sleep is one of the great mysteries of life. We spend a third of our life sleeping without awareness of the outside world. Part of this time, during dreams, we have a bizarre cognitive activity disconnected from reality and guided by internal stimuli. In the last 70years, as a result of basic research, there has been a remarkable increase in the knowledge of the physiology of sleep. Some of this knowledge has been transferred to the medical practice, where about 80 different sleep disturbances have been described. In most mammals (including humans) and birds, two sleep states can be readily distinguished: rapid eye movement sleep and nonrapid eye movement sleep. Polysomnography (PSG) is the basic tool used to recognize and characterize these behavioral states, and to explore brain activity during sleep. In the present work, we present a brief review of the main PSG procedures and data analysis in clinical and humans research settings, as well as in animal models.

Original languageEnglish
Title of host publicationMethodological Approaches for Sleep and Vigilance Research
EditorsEric Murillo Rodriguez
Number of pages16
ISBN (Electronic)9780323852357
ISBN (Print)9780323903349
Publication statusPublished - 2022

Bibliographical note

This study was supported by the “Programa de Desarrollo de las Ciencias Básicas, PEDECIBA” from Uruguay.


  • Coherence
  • EEG
  • NREM
  • Power spectrum
  • REM
  • Sleep
  • Slow wave sleep


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