Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1—allergic asthma

G. K. Scadding; M. McDonald; V. Backer; G. Scadding; M. Bernal-Sprekelsen; D. M. Conti; E. De Corso; Z. Diamant; C. Gray; C. Hopkins; M. Jesenak; P. Johansen; J. Kappen; J. Mullol; D. Price; S. Quirce; S. Reitsma; S. Salmi; B. Senior; J. P. Thyssen; U. Wahn; P. W. Hellings

doi:10.3389/falgy.2023.1291185

Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1—allergic asthma

G. K. Scadding, M. McDonald, V. Backer, G. Scadding, M. Bernal-Sprekelsen, D. M. Conti^* (Corresponding Author), E. De Corso, Z. Diamant, C. Gray, C. Hopkins, M. Jesenak, P. Johansen, J. Kappen, J. Mullol, D. Price, S. Quirce, S. Reitsma, S. Salmi, B. Senior, J. P. ThyssenU. Wahn, P. W. Hellings

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in 2019, is a significant burden to suffers and to society. It is the most common chronic disease in children and represents one of the major causes for years lived with disability. Significant efforts are made by organizations such as WHO in improving the diagnosis, treatment and monitoring of asthma. However asthma prevention has been less studied. Currently there is a concept of pre- diabetes which allows a reduction in full blown diabetes if diet and exercise are undertaken. Similar predictive states are found in Alzheimer's and Parkinson's diseases. In this paper we explore the possibilities for asthma prevention, both at population level and also investigate the possibility of defining a state of pre-asthma, in which intensive treatment could reduce progression to asthma. Since asthma is a heterogeneous condition, this paper is concerned with allergic asthma. A subsequent one will deal with late onset eosinophilic asthma.

Original language	English
Article number	1291185
Number of pages	16
Journal	Frontiers in Allergy
Volume	4
Early online date	30 Jan 2024
DOIs	https://doi.org/10.3389/falgy.2023.1291185
Publication status	Published - 30 Jan 2024

Bibliographical note

Funding
The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.

Data Availability Statement

The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.

Keywords

pre-asthma
asthma
quality of life
asthma natural history
predisposition
risk factors

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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© 2024 Scadding, McDonald, Backer, Scadding, Bernal-Sprekelsen, Conti, De Corso, Diamant, Gray, Hopkins, Jesenak, Johansen, Kappen, Mullol, Price, Quirce, Reitsma, Salmi, Senior, Thyssen, Wahn and Hellings. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.https://creativecommons.org/licenses/by/4.0/
Final published version, 1.01 MBLicence: CC BY

Cite this

Scadding, G. K., McDonald, M., Backer, V., Scadding, G., Bernal-Sprekelsen, M., Conti, D. M., De Corso, E., Diamant, Z., Gray, C., Hopkins, C., Jesenak, M., Johansen, P., Kappen, J., Mullol, J., Price, D., Quirce, S., Reitsma, S., Salmi, S., Senior, B., ... Hellings, P. W. (2024). Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1—allergic asthma. Frontiers in Allergy, 4, Article 1291185. https://doi.org/10.3389/falgy.2023.1291185

Scadding, GK, McDonald, M, Backer, V, Scadding, G, Bernal-Sprekelsen, M, Conti, DM, De Corso, E, Diamant, Z, Gray, C, Hopkins, C, Jesenak, M, Johansen, P, Kappen, J, Mullol, J, Price, D, Quirce, S, Reitsma, S, Salmi, S, Senior, B, Thyssen, JP, Wahn, U & Hellings, PW 2024, 'Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1—allergic asthma', Frontiers in Allergy, vol. 4, 1291185. https://doi.org/10.3389/falgy.2023.1291185

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abstract = "Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in 2019, is a significant burden to suffers and to society. It is the most common chronic disease in children and represents one of the major causes for years lived with disability. Significant efforts are made by organizations such as WHO in improving the diagnosis, treatment and monitoring of asthma. However asthma prevention has been less studied. Currently there is a concept of pre- diabetes which allows a reduction in full blown diabetes if diet and exercise are undertaken. Similar predictive states are found in Alzheimer's and Parkinson's diseases. In this paper we explore the possibilities for asthma prevention, both at population level and also investigate the possibility of defining a state of pre-asthma, in which intensive treatment could reduce progression to asthma. Since asthma is a heterogeneous condition, this paper is concerned with allergic asthma. A subsequent one will deal with late onset eosinophilic asthma.",

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Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1—allergic asthma

Abstract

Bibliographical note

Data Availability Statement

Keywords

UN SDGs

Access to Document

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Cite this