Predictive and prognostic value of LSP1 rs3817198 in sporadic breast cancer in northeastern population of Iran

Fahimeh Afzaljavan, Atefeh Moezzi, Elham Vahednia, Asma Khorshid Shamshiri, Fatemeh Vakili, Fatemeh Homaei Shandiz, Alireza Pasdar* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Being the most common malignancy affecting patient's lifetime worldwide, the diagnosis of breast cancer especially in its early stages is of paramount importance (Wang, 2017). It has been reported that about 22.6 in 100,000 Iranian women would develop the primary breast cancer during their lifetime (Jazayeri et al., 2015). As a heterogeneous disease, which could be influenced through genetic or epigenetic mechanisms as well as environmental risk factors, characterization and treatment of breast cancer could be extremely demanding (Chen et al., 2011; Turnbull et al., 2011; Byler et al., 2014). Therefore, recent studies have been emphasizing on finding the potential risk factors contributing to the development, progression and response to the therapy of the disease (Ambrosone et al., 2015).
Original languageEnglish
Article number104514
Number of pages8
JournalExperimental and molecular pathology
Volume116
Early online date29 Jul 2020
DOIs
Publication statusPublished - 31 Oct 2020

Bibliographical note

Acknowledgements:
The authors thank all participants in this research. We would also like to thank the Student Research Committee, Mashhad University of Medical Sciences and Omid hospital (Mashhhad, Iran) to support the project.
Funding:
This work was financially supported by Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran, under Grant 961686.

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