Presentation of trypanosomiasis in nkhotakota

John Chisi*, Arister Nkhoma, Jeremy Sternberg

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


In 2002, we identified 28 people in Nkhotakota District who were suffering from Human African Trypanosomiasis (HAT). Sixteen of these were identified when they presented to the District Hospital with a febrile illness. The remaining twelve were identified through a rural cross-sectional survey, in which 500 people were visited in their homes, persons found to be febrile, were examined by blood film microscopy. Of the 28 people, 50% (14) presented within a month of the onset of symptoms. Sixteen (57%) had splenomegaly, and 24 were anaemic ([Hb] <12 g/dl). Four patients died (14%), of which two were in the late stage of the disease. None of the patients recall having a chancre that could be attributed to the bite of tsetse flies. 9 out of 28 (32%) reported illness longer than 90 days. Of the 9 patients 6 (66%) of them remained in the early stage after reporting illness of 180 days. This study reports on the prevalence and clinical features of Trypansoma brucei rhodesiense infection in a endemic district in Malawi.
Original languageEnglish
Pages (from-to)140-141
Number of pages3
JournalMalawi Medical Journal
Issue number4
Publication statusPublished - Dec 2007

Bibliographical note

We are grateful to the Wellcome Trust for funding this
project. Our gratitude is also extended to Kathrin BroetzChisi for reviewing the manuscript.


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