Primürstruktur der Adipokinetischen Hormone II von Heuschrecken

Translated title of the contribution: Primary Structures of Locust Adipokinetic Hormones II

Karl Siegert, Peter Morgan, William Mordue

Research output: Contribution to journalArticlepeer-review

127 Citations (Scopus)


Adipokinetic hormones II from corpora cardiaca of the locusts Schistocerca gregaria and Locusta migratoria, respectively, have been isolated and their primary structures elucidated. Both octapeptides are N-terminally blocked by a 5-oxoproline (pyroglutamate) residue and had to be cleaved by 5-oxoprolyl-peptidase to make them available for the Edman degradation method carried out with a gas-phase sequencer. The C- termini are blocked as both peptides are not cleaved by carboxypeptidase A; the presence of C-terminal amide groups is very likely. AKHII (S. gregaria) Glu-Leu-Asn-Phe-Ser-Thr-Gly-Trp-NHi AKHII (L. migratoria) Glu-Leu-Asn-Phe-Ser-Ala-Gly-Trp-NH2.

Translated title of the contributionPrimary Structures of Locust Adipokinetic Hormones II
Original languageOther
Pages (from-to)723-728
Number of pages6
JournalBiological Chemistry Hoppe-Seyler
Issue number2
Publication statusPublished - 1 Jan 1985


  • gas-phase sequencing
  • Locusts
  • primary structure
  • reversed-phase high-performance liquid chromatography


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