Primary thyroid leiomyosarcoma: a diagnostic and therapeutic challenge

Mohammed Talha Bashir, Tom Bradish* (Corresponding Author), Usman Rasul, Muhammad Shakeel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Leiomyosarcoma is a malignant mesenchymal tumour of smooth muscle origin. It is extremely rare as a primary thyroid cancer with only 33 cases previously described in the literature. We present the case of a 69-year-old Caucasian man who presented with a 5-month history of left cervical lymphadenopathy and a suspicious mass in the left thyroid lobe on ultrasound scan. Left hemithyroidectomy confirmed the diagnosis of leiomyosarcoma. A review of current understanding and approaches to management of this rare condition are discussed. [Abstract copyright: © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions.
Original languageEnglish
Article numbere236399
JournalBMJ Case Reports
Issue number4
Early online date28 Apr 2021
Publication statusPublished - 28 Apr 2021


  • ear
  • nose and throat/otolaryngology
  • pathology
  • thyroid disease


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