Properties of the copper(II)-histidine complex obtained after dialysis of human plasma with histidine

Tony Venelinov, Sonia Arpadjan, Irina Karadjova, John Hamilton Beattie

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

The copper(II)-histidine complex obtained following dialysis of human plasma with histidine was investigated using various types of extraction systems and ion exchange resins. According to the results obtained, the Cu(II)-histidine complex formed under the dialysis conditions has one positive charge. Preconcentration of copper from the dialysis solution was achieved by its extraction as a dithiocarbamate complex and by sorption on cation-exchange resin or onto chelate sorbent.
Original languageEnglish
Pages (from-to)105-112
Number of pages8
JournalActa Pharmaceutica
Volume56
Issue number1
Publication statusPublished - 1 Mar 2006

Keywords

  • Adsorption
  • Adult
  • Copper
  • Dialysis
  • Histidine
  • Humans
  • Male
  • Middle Aged

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