Proteomic analysis of plasma, platelets and PBMC in nutritional intervention studies

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The use of proteomics as a valuable tool in nutrition research is discussed in this chapter. Proteome analysis of plasma and blood cells such as platelets and peripheral blood mononuclear cells (PBMC) can identify thousands of proteins that: potentially provide valuable new biomarkers for health; reveal early indications of disease risk; assist in establishing dietary responders from non-responders; and enable discovery of mechanisms of action for beneficial food components. The different proteomic techniques are also described with their corresponding advantages and disadvantages in nutrition research.
Original languageEnglish
Title of host publicationDesign of human nutrigenomic studies
EditorsSiân Astley , Linda Penn
Place of PublicationWageningen
PublisherWageningen Academic Publishers
Pages55-64
Number of pages10
ISBN (Print)978-90-8686-094-4 , 908686094X
Publication statusPublished - 1 Jul 2009

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