Purealidin S and Purpuramine J, Bromotyrosine Alkaloids from the Fijian Marine Sponge Druinella sp.

Jioji Natadra Tabudravu; Marcel Jaspars

doi:10.1021/np020275n

Purealidin S and Purpuramine J, Bromotyrosine Alkaloids from the Fijian Marine Sponge Druinella sp.

Jioji Natadra Tabudravu, Marcel Jaspars

Chemistry

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.

Original language	English
Pages (from-to)	1798-1801
Number of pages	3
Journal	Journal of Natural Products
Volume	65
DOIs	https://doi.org/10.1021/np020275n
Publication status	Published - 2002

Keywords

DIBROMOTYROSINE-DERIVED METABOLITE
BROMINATED TYROSINE METABOLITES
PSAMMAPLYSILLA-PURPUREA
PSEUDOCERATINA-PURPUREA
VERONGIDA SPONGES
AIOLOCHROIA-CRASSA
DERIVATIVES
CHEMISTRY
CYANOFORMAMIDE
CONSTITUENTS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/np020275n

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title = "Purealidin S and Purpuramine J, Bromotyrosine Alkaloids from the Fijian Marine Sponge Druinella sp.",

abstract = "Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.",

keywords = "DIBROMOTYROSINE-DERIVED METABOLITE, BROMINATED TYROSINE METABOLITES, PSAMMAPLYSILLA-PURPUREA, PSEUDOCERATINA-PURPUREA, VERONGIDA SPONGES, AIOLOCHROIA-CRASSA, DERIVATIVES, CHEMISTRY, CYANOFORMAMIDE, CONSTITUENTS",

author = "Tabudravu, {Jioji Natadra} and Marcel Jaspars",

year = "2002",

doi = "10.1021/np020275n",

language = "English",

volume = "65",

pages = "1798--1801",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "American Chemical Society",

}

TY - JOUR

T1 - Purealidin S and Purpuramine J, Bromotyrosine Alkaloids from the Fijian Marine Sponge Druinella sp.

AU - Tabudravu, Jioji Natadra

AU - Jaspars, Marcel

PY - 2002

Y1 - 2002

N2 - Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.

AB - Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.

KW - DIBROMOTYROSINE-DERIVED METABOLITE

KW - BROMINATED TYROSINE METABOLITES

KW - PSAMMAPLYSILLA-PURPUREA

KW - PSEUDOCERATINA-PURPUREA

KW - VERONGIDA SPONGES

KW - AIOLOCHROIA-CRASSA

KW - DERIVATIVES

KW - CHEMISTRY

KW - CYANOFORMAMIDE

KW - CONSTITUENTS

U2 - 10.1021/np020275n

DO - 10.1021/np020275n

M3 - Article

SN - 0163-3864

VL - 65

SP - 1798

EP - 1801

JO - Journal of Natural Products

JF - Journal of Natural Products

ER -

Purealidin S and Purpuramine J, Bromotyrosine Alkaloids from the Fijian Marine Sponge Druinella sp.

Abstract

Keywords

UN SDGs

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