Risk Factors for Pre-Eclampsia: A Study in Tehran, Iran

Maryam Kashanian*, Hamid Reza Baradaran, Shohreh Bahasadri, Razieh Alimohammadi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


This study evaluated some risk factors for pre-eclampsia, which is one of the most problematic complications of pregnancy. This was a retrospective case control study conducted on 318 pre-eclamptic women (case group) and 318 women who were normotensive at the time of delivery as the control group. Evaluated factors were: maternal age, gestational age, nuliparity, mother's educational status, maternal body mass index (EMI), maternal hemoglobin and blood Rh, familial history of pre-eclampsia, history of pre-eclampsia in a previous pregnancy, marital relations, urinary infection (UTI) during the present pregnancy, season of delivery, and method of contraception. Risk factors for pre-eclampsia were: UTI (P=0.04); history of pre-eclampsia during previous pregnancy (P=0.003), and winter season (P=0.001). Maternal age of more than 20 years, high educational status of mother, parity more than one, and oral contraceptive pills were protective for pre-eclampsia. After adjusting for all possible confounding factors using multiple logistic regression, only preexisting pre-eclampsia (P=0.004) was a risk factor, whereas parity more than three (P=0.007) and anemia (P=0.01) were protective for pre-eclampsia. The rate of cesarean delivery was more common in the pre-eclamptic group (245 cases, 77%) than the control group (85 cases, 26.7%). The one minute Apgar score of neonates less than 8 was more common in the case group (28.6% vs. 47.4%, P

Original languageEnglish
Pages (from-to)412-415
Number of pages4
JournalArchives of Iranian Medicine
Issue number6
Publication statusPublished - Nov 2011


  • Gestational age
  • Pre-eclampsia
  • Pregnancy induced hypertension
  • Risk factors


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