SERRS immunoassay for quantitative human CRP analysis

Fiona Margaret Campbell; Andrew Ingram; Paul Monaghan; Jon Cooper; Naveed Sattar; P. David Eckersall; Duncan Graham

doi:10.1039/b808087a

SERRS immunoassay for quantitative human CRP analysis

Fiona Margaret Campbell, Andrew Ingram, Paul Monaghan, Jon Cooper, Naveed Sattar, P. David Eckersall, Duncan Graham

The Rowett Institute of Nutrition and Health

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

SERRS has been used for the first time for the measurement of C-reactive protein (CRP) in an immunoassay. CRP, a biological marker for the diagnosis of infection and inflammation, is quantified in an ELISA using conventional reagents, but the usual colorimetric detection step is replaced by SERRS detection, offering improved sensitivity and potential for multiplexing analysis.

Original language	English
Pages (from-to)	1355-1357
Number of pages	3
Journal	Analyst
Volume	133
Issue number	10
Early online date	25 Jun 2008
DOIs	https://doi.org/10.1039/b808087a
Publication status	Published - 1 Oct 2008

Keywords

C-reactive protein
resonance-raman-scattering
coronary-heart-disease
epidemiologic applications
cardiovascular-disease
spectroscopy
inflammation
silver
nanoparticles
association

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/b808087a

Cite this

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abstract = "SERRS has been used for the first time for the measurement of C-reactive protein (CRP) in an immunoassay. CRP, a biological marker for the diagnosis of infection and inflammation, is quantified in an ELISA using conventional reagents, but the usual colorimetric detection step is replaced by SERRS detection, offering improved sensitivity and potential for multiplexing analysis.",

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AU - Campbell, Fiona Margaret

AU - Ingram, Andrew

AU - Monaghan, Paul

AU - Cooper, Jon

AU - Sattar, Naveed

AU - Eckersall, P. David

AU - Graham, Duncan

PY - 2008/10/1

Y1 - 2008/10/1

N2 - SERRS has been used for the first time for the measurement of C-reactive protein (CRP) in an immunoassay. CRP, a biological marker for the diagnosis of infection and inflammation, is quantified in an ELISA using conventional reagents, but the usual colorimetric detection step is replaced by SERRS detection, offering improved sensitivity and potential for multiplexing analysis.

AB - SERRS has been used for the first time for the measurement of C-reactive protein (CRP) in an immunoassay. CRP, a biological marker for the diagnosis of infection and inflammation, is quantified in an ELISA using conventional reagents, but the usual colorimetric detection step is replaced by SERRS detection, offering improved sensitivity and potential for multiplexing analysis.

KW - C-reactive protein

KW - resonance-raman-scattering

KW - coronary-heart-disease

KW - epidemiologic applications

KW - cardiovascular-disease

KW - spectroscopy

KW - inflammation

KW - silver

KW - nanoparticles

KW - association

U2 - 10.1039/b808087a

DO - 10.1039/b808087a

M3 - Article

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VL - 133

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JO - Analyst

JF - Analyst

IS - 10

ER -

SERRS immunoassay for quantitative human CRP analysis

Abstract

Keywords

UN SDGs

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