Severe Asthma Global Evaluation (SAGE): An Electronic Platform for Severe Asthma

Eve Denton (Corresponding Author), Fiona Hore-Lacy, Naghmeh Radhakrishna, Annie Gilbert, TunnRen Tay, Joy Lee, Eli Dabscheck, Erin S Harvey, Lakmini Bulathsinhala, James Fingleton, David Price, Peter G. Gibson, Robyn O'Hehir, Mark Hew

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)


Severe asthma is complex and heterogeneous; ad hoc outpatient assessment can be suboptimal. Systematic evaluation improves outcomes and is recommended by international guidelines. Electronic templates improve physician performance and clinical processes, and may be useful in severe asthma systematic evaluation. We developed the Severe Asthma Global Evaluation (SAGE) electronic platform to streamline this process, via Research Electronic Data Capture (REDCap). It incorporates: a questionnaire battery for patient completion before clinical consultation; asthma and comorbidity modules; a clinical summary page in an asthma management module; a nurse educator module; a structured panel discussion record; and an automatically generated report incorporating all key data. SAGE incorporates 282 clinician input fields, with a typical consultation requiring completion of 169. To streamline the process SAGE contains 34 autocalculations and 20 decision support tools. It incorporates all 95 core variables of the International Severe Asthma Registry, with which it is directly compatible. SAGE improves symptom control and exacerbations in patients with difficult asthma. In conclusion, we developed and validated an electronic platform that facilitates a comprehensive but streamlined systematic evaluation of severe asthma that is available for free download via REDCap. Its use enhances management of patients with severe asthma and facilitates audit and international research collaboration.

Original languageEnglish
Pages (from-to)1440-1449
Number of pages10
JournalThe journal of allergy and clinical immunology. In practice
Issue number5
Early online date4 Apr 2019
Publication statusPublished - May 2019


  • asthma
  • Systematic assessment
  • Difficult asthma
  • Clinical decision support systems
  • REDCap
  • Severe asthma
  • Electronic platform
  • Asthma
  • CARE


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