Sexual dimorphism in campylobacteriosis

N. J. C. Strachan, R. O. Watson, V. Novik, D. Hofreuter, I. D. Ogden, J. E. Galan

Research output: Contribution to journalArticle

29 Citations (Scopus)


Sexual dimorphism in infectious diseases whereby disease incidence is more prevalent in one gender has been reported repeatedly in the scientific literature. Both behavioural and physiological differences have been suggested as a cause of this gender bias but there is a paucity of data to support either of these viewpoints. Here it is hypothesized that for campylobacteriosis physiological factors play an important role in the higher incidence in males. We demonstrate In the human population (from several countries in three continents) that this bias exists in young children (< 1 year) where behavioural differences between genders are likely to be minimal. Further we demonstrate this difference in an animal model where both infection rates and shedding rates of the orgainsm are greater in male mice.

Original languageEnglish
Pages (from-to)1492-1495
Number of pages4
JournalEpidemiology and Infection
Issue number11
Early online date7 Dec 2007
Publication statusPublished - Nov 2008


  • jejuni infection
  • United-States
  • gender
  • mice


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