Simultaneous Determination of Stable Carbon, Oxygen, and Hydrogen Isotopes in Cellulose

N.J. Loader, F.A. Street-Perrott, T.J. Daley, P.D.M. Hughes, A. Kimak, T. Levanič, G. Mallon, D. Mauquoy, I. Robertson, T.P. Roland, S. van Bellen, M.M. Ziehmer, M. Leuenberger

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


A technological development is described through which the stable carbon-, oxygen-, and nonexchangeable hydrogen-isotopic ratios (δ13C,
δ18O, δ2 H) are determined on a single carbohydrate (cellulose) sample with
precision equivalent to conventional techniques (δ13C 0.15‰, δ18O 0.30‰,
δ2 H 3.0‰). This triple-isotope approach offers significant new research
opportunities, most notably in physiology and medicine, isotope biogeochemistry,
forensic science, and palaeoclimatology, when isotopic analysis of a common sample is desirable or when sample material is limited.
Original languageEnglish
Pages (from-to)376-380
Number of pages5
JournalAnalytical Chemistry
Issue number1
Early online date11 Dec 2014
Publication statusPublished - 2015

Bibliographical note

This study was supported by UK NERC Grants NE/G019673/
1, NE/I022809/1, NE/I022981/1, NE/I022833/1, and NE/
I023104/1, iTREE (SNSF Sinergia project 136295), and the
Climate Change Consortium of Wales (C3W). We thank our
colleagues in the EU “Millennium” Project (Roderick Bale,
Rhodri Griffiths, Hö gne Jungner, Danny McCarroll, Hanspeter
Moret, Peter Nyfeler, Eloni Sonninen, and Giles Young) for
support and Dan Charman for “gentle encouragement”.


  • Hydrogen Isotopes
  • Cellulose


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